Department of Ophthalmology, Mass Eye and Ear, Boston, Massachusetts.
Department of Ophthalmology, Duke Eye Center, Durham, North Carolina.
Curr Opin Ophthalmol. 2023 Mar 1;34(2):168-175. doi: 10.1097/ICU.0000000000000925. Epub 2022 Nov 7.
The purpose of this review is to examine contemporary techniques for detecting the progression of glaucoma. We provide a general overview of detection principles and review evidence-based diagnostic strategies and specific considerations for detecting glaucomatous progression in patients with mild, moderate and severe disease.
Diagnostic techniques and technologies for glaucoma have dramatically evolved in recent years, affording clinicians an expansive toolkit with which to detect glaucoma progression. Each stage of glaucoma, however, presents unique diagnostic challenges. In mild disease, either structural or functional changes can develop first in disease progression. In moderate disease, structural or functional changes can occur either in tandem or in isolation. In severe disease, standard techniques may fail to detect further disease progression, but such detection can still be measured using other modalities.
Detecting disease progression is central to the management of glaucoma. Glaucomatous progression has both structural and functional elements, both of which must be carefully monitored at all disease stages to determine when interventions are warranted.
本文旨在探讨当前青光眼进展检测的相关技术。我们对检测原理进行了概述，并回顾了基于证据的诊断策略，以及在轻度、中度和重度疾病患者中检测青光眼进展时的具体考虑因素。
近年来，青光眼的诊断技术和设备有了显著的发展，为临床医生提供了广泛的工具来检测青光眼的进展。然而，青光眼的每个阶段都存在独特的诊断挑战。在轻度疾病中，结构或功能变化可能首先出现在疾病进展中。在中度疾病中，结构或功能变化可能同时或单独发生。在重度疾病中，标准技术可能无法检测到进一步的疾病进展，但仍可以使用其他模式来测量这种检测。
检测疾病进展是青光眼管理的核心。青光眼进展既有结构因素也有功能因素，在所有疾病阶段都必须仔细监测这两个因素，以确定何时需要干预。
