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在重症监护环境中实施谵妄指南五年后持续遵循该指南:一项回顾性队列研究。

Sustained adherence to a delirium guideline five years after implementation in an intensive care setting: A retrospective cohort study.

作者信息

van Bochove-Waardenburg Marlies, van der Jagt Mathieu, de Man-van Ginkel Janneke, Ista Erwin

机构信息

Department of Intensive Care, Erasmus MC, Erasmus University Medical Center Rotterdam, The Netherlands; Department of Nursing Science, Program in Clinical Health Science, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.

Department of Intensive Care, Erasmus MC, Erasmus University Medical Center Rotterdam, The Netherlands.

出版信息

Intensive Crit Care Nurs. 2023 Jun;76:103398. doi: 10.1016/j.iccn.2023.103398. Epub 2023 Jan 31.

Abstract

OBJECTIVE

To explore the level of sustained adherence to a delirium guideline in a university intensive care unit setting five years after cessation of a multifaceted implementation program conducted between April 2012 and February 2015.

RESEARCH METHODOLOGY/DESIGN: A quantitative retrospective cohort study was conducted using the medical records of all eligible patients admitted to the intensive care unit from November 2019 to February 2020.

SETTING

Four adult intensive care units in a university hospital.

MAIN OUTCOME MEASURES

Primary outcome is adherence to seven performance indicators indicated in the guideline being: light sedation days, mobilisation, physical therapy, analgesics use, delirium and sedation screening and avoiding benzodiazepines. Clinical patient outcomes such as Intensive care unit stay and prevalence of delirium were also collected. Data were compared with the results of the original implementation study's using descriptive statistics and Kruskal-wallis and Chi-square tests.

RESULTS

Data of 236 patients were included. The most notable decrease in adherence concerned 'number of light sedation days' (-28 %). Adherence to three indicators had increased: 'number of days receiving out-of-bed mobilisation' (+11 %); 'number of days receiving physical therapy' (+9%); and 'use of analgesics' (+12 %). Comparison of clinical outcomes showed an increased intensive care unit length-of-stay from 3 to 5 days (P < 0.001). Prevalence of delirium increased over five years from 41 % to 43 % of patients while delirium duration decreased from a median of 3 days to a median of 2 days.

CONCLUSION

Five years after ceasing of implementation efforts regarding the delirium guideline, partial sustainability has been achieved. The decrease in adherence to 'number of light sedation days' could have contributed to the increased length-of-stay on the intensive care unit.

IMPLICATIONS FOR CLINICAL PRACTICE

After implementation, routine monitoring of performance indicators is required to evaluate the level of sustainment. Further, revisiting reasons for decrease in guideline adherence when contextual changes occur. Reassessment of the perceived barriers and facilitators can guide adaptations to sustain, or even improve, adherence.

摘要

目的

在2012年4月至2015年2月实施的多方面实施计划停止五年后,探讨大学重症监护病房环境中对谵妄指南的持续遵守程度。

研究方法/设计:采用2019年11月至2020年2月入住重症监护病房的所有符合条件患者的病历进行定量回顾性队列研究。

研究地点

一所大学医院的四个成人重症监护病房。

主要观察指标

主要结果是对指南中指出的七个绩效指标的遵守情况,即:轻度镇静天数、活动、物理治疗、镇痛药使用、谵妄和镇静筛查以及避免使用苯二氮䓬类药物。还收集了临床患者结局,如重症监护病房住院时间和谵妄患病率。使用描述性统计以及Kruskal-Wallis和卡方检验将数据与原始实施研究的结果进行比较。

结果

纳入了236例患者的数据。遵守情况下降最明显的是“轻度镇静天数”(-28%)。对三个指标的遵守情况有所增加:“下床活动天数”(+11%);“接受物理治疗天数”(+9%);以及“镇痛药使用”(+12%)。临床结局比较显示,重症监护病房住院时间从3天增加到5天(P<0.001)。谵妄患病率在五年内从41%上升至43%,而谵妄持续时间从中位数3天降至中位数2天。

结论

在停止关于谵妄指南的实施工作五年后,已实现部分可持续性。对“轻度镇静天数”遵守情况的下降可能导致了重症监护病房住院时间的增加。

对临床实践的启示

实施后,需要对绩效指标进行常规监测以评估维持水平。此外,当情况发生变化时,重新审视指南遵守情况下降的原因。对感知到的障碍和促进因素进行重新评估可以指导调整,以维持甚至提高遵守情况。

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