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延长检测期是否能改善结直肠癌筛查?

[Does prolonging the test period improve screening for colorectal cancer?].

作者信息

Hammes P H, Gnauck R

机构信息

Deutsche Klinik für Diagnostik, Wiesbaden.

出版信息

Z Gastroenterol. 1987 Sep;25(9):607-11.

PMID:3673146
Abstract

Prolongation of Haemoccult-screening from 3 to 6 days in 3540 out-patients resulted in a rise of the positivity rate from 4.1 to 6.75%. This was accompanied by an increase of the detection rate by 10% in cancers and 25% in large adenomas. The predictive value of a positive test for colorectal neoplasia (carcinoma and large polyps together) dropped from 26.7 to 20.9%. More data are needed before general recommendation for change from the standard 3-day-test period can be given.

摘要

对3540名门诊患者将潜血筛查时间从3天延长至6天,结果阳性率从4.1%升至6.75%。同时,癌症的检出率提高了10%,大腺瘤的检出率提高了25%。结直肠肿瘤(癌和大息肉)阳性检测的预测值从26.7%降至20.9%。在能够给出关于从标准的3天检测期改变的普遍建议之前,还需要更多数据。

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