Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, Thailand.
Ocul Immunol Inflamm. 2024 Feb;32(2):218-225. doi: 10.1080/09273948.2023.2165110. Epub 2023 Feb 2.
To analyze characteristics, etiology, and outcome of retinal vasculitis in Central Thailand.
A retrospective cohort study.
Retinal vasculitis was found in 10% of uveitis, 74 from 741 uveitis, noninfectious (64.9%) and infectious group (35.1%). The most common cause was Behcet's disease (48.6%). Behcet's disease was the most common cause of all types of vascular leakage on angiography, including capillary (80.4%), venous (56.3%), and arterial leakage (56%). Final visual acuity was 0.86 ± 0.97 logMAR. Cataract was the most frequent complication (42.5%). Acute clinical course ( = .025) and retinal neovascularization ( = .031) were associated with infectious group. Forty-three percent of vasculitis complicated by ischemia required photocoagulation (33%) and anti-VEGF injection (17%). Furthermore, 17% of vasculitis underwent vitrectomy.
One-half of the retinal vasculitis in Central Thailand were Behcet's disease. Acute onset and retinal neovascularization may suggest infectious etiology. Retinal ischemia should be cautious and undergo early interventions to prevent sight-threatening complications.
分析泰国中部视网膜血管炎的特征、病因和转归。
回顾性队列研究。
在 741 例葡萄膜炎患者中，有 10%的患者存在视网膜血管炎，共 74 例。非感染性（64.9%）和感染性（35.1%）两组病因构成比差异有统计学意义。最常见的病因是贝赫切特病（48.6%）。贝赫切特病是所有类型血管渗漏的最常见病因，包括毛细血管（80.4%）、静脉（56.3%）和动脉渗漏（56%）。最终视力为 0.86±0.97 logMAR。白内障是最常见的并发症（42.5%）。急性临床病程（ = 0.025）和视网膜新生血管（ = 0.031）与感染性病因有关。43%的血管炎合并缺血需要光凝（33%）和抗 VEGF 注射（17%）。此外，17%的血管炎患者行玻璃体切除术。
泰国中部一半的视网膜血管炎是由贝赫切特病引起的。急性发作和视网膜新生血管可能提示感染性病因。视网膜缺血应谨慎，并尽早进行干预，以防止威胁视力的并发症。
