Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
Can J Cardiol. 2023 Jun;39(6):779-792. doi: 10.1016/j.cjca.2023.01.022. Epub 2023 Jan 31.
After the first confirmed case in 2019, COVID-19 rapidly spread worldwide and overwhelmed the medical community. In the intervening time, we have learned about COVID-19's clinical manifestations and have developed effective therapies and preventative vaccines. Severe COVID-19 infection is associated with many cardiovascular disorders in the acute phase, and patients recovered from illness can also manifest long-term sequelae, including long COVID syndrome. Furthermore, severe acute respiratory syndrome-related coronavirus-2 messenger RNA (mRNA) vaccination can trigger rare cases of myopericarditis. We have gained significant knowledge of the acute and long-term cardiovascular complications of COVID-19- and mRNA vaccine-associated myocarditis through clinical and investigative studies using cardiac imaging. In this review, we describe how cardiovascular imaging can be used to understand the cardiovascular complications and cardiac injury associated with acute COVID-19 infection, review the imaging findings in patients recovered from illness, and discuss the role and limitations of cardiac imaging in COVID-19 mRNA vaccine-associated myocarditis.
自 2019 年首例确诊病例以来,COVID-19 迅速在全球范围内传播,使医疗界不堪重负。在这期间,我们已经了解了 COVID-19 的临床表现,并开发了有效的治疗方法和预防疫苗。严重的 COVID-19 感染与急性期的许多心血管疾病有关,从疾病中康复的患者也可能表现出长期后遗症,包括长 COVID 综合征。此外,与严重急性呼吸综合征相关的冠状病毒-2 信使 RNA(mRNA)疫苗接种会引发罕见的心肌炎病例。我们通过使用心脏成像的临床和研究,获得了有关 COVID-19 和 mRNA 疫苗相关心肌炎的急性和长期心血管并发症的大量知识。在这篇综述中,我们描述了心血管成像如何用于了解与急性 COVID-19 感染相关的心血管并发症和心脏损伤,回顾了从疾病中康复的患者的影像学发现,并讨论了心脏成像在 COVID-19 mRNA 疫苗相关心肌炎中的作用和局限性。