中文版本孤独症诊断观察量表-通用的心理计量特性。
Psychometric properties of the Mandarin version of the autism diagnostic observation Schedule-Generic.
机构信息
Department of Psychiatry, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Department of Psychiatry, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan; The Margaret and Wallace McCain Centre for Child, Youth & Family Mental Health and Azrieli Adult Neurodevelopmental Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry and Autism Research Unit, The Hospital for Sick Children, Toronto, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Canada; Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.
出版信息
J Formos Med Assoc. 2023 Jul;122(7):574-583. doi: 10.1016/j.jfma.2023.01.008. Epub 2023 Jan 31.
BACKGROUND/PURPOSE: The diagnosis of autism spectrum disorder (ASD), involving multiple components of clinical assessments, is challenging. The Autism Diagnostic Observation Schedule-Generic (ADOS-G), one of the standardized and validated instruments for ASD diagnostic evaluation, has been widely used in many countries. With the preparation of the Mandarin version of the ADOS-G (Mandarin-ADOS-G), this study aims to examine its psychometric properties, including reliability and validity.
METHODS
The sample included 554 individuals clinically diagnosed with ASD (477 males, 86.1%) and 50 typically developing (TD) individuals (29 males, 58.0%) who were assessed with different modules of the Mandarin-ADOS-G between 4.1 and 34.0 years old with a mean age of 13.0 years (Module 1, n = 40; Module 2, n = 46; Module 3, n = 275; Module 4, n = 243). We evaluated the inter-rater reliability, test-retest reliability, internal consistency, and concurrent validity with the Chinese Autism Diagnostic Interview-Revised (ADI-R) and Social Responsiveness Scale (SRS) caregiver-report and self-report forms. The discriminative validity of Mandarin-ADOS-G was also examined.
RESULTS
The Mandarin-ADOS-G demonstrated good inter-rater reliability (agreement of ADOS classification 0.91), good test-retest reliability (intraclass correlations 0.55-0.73), and low to high good internal consistency (Cronbach's alpha 0.27-0.86). The concurrent validity showed significant correlations with ADI-R (Pearson correlations 0.22-0.37) and the SRS caregiver-report form (Pearson correlations 0.15-0.23). Moreover, all Mandarin-ADOS-G domains successfully differentiated autistic individuals from TD individuals (all p-values <0.001).
CONCLUSION
The Mandarin-ADOS-G is a reliable and valid instrument for assisting the diagnosis of ASD in the Mandarin-speaking population.
背景/目的：自闭症谱系障碍（ASD）的诊断涉及到临床评估的多个组成部分，具有挑战性。自闭症诊断观察量表-通用版（ADOS-G）是 ASD 诊断评估的标准化和验证工具之一，已在许多国家广泛使用。随着 Mandarin-ADOS-G 的准备，本研究旨在检验其心理测量特性，包括可靠性和有效性。
方法
样本包括 554 名临床诊断为 ASD 的个体（477 名男性，86.1%）和 50 名典型发育（TD）个体（29 名男性，58.0%），他们在 4.1 至 34.0 岁之间接受了 Mandarin-ADOS-G 的不同模块评估，平均年龄为 13.0 岁（模块 1，n=40；模块 2，n=46；模块 3，n=275；模块 4，n=243）。我们评估了 Mandarin-ADOS-G 的同评者间信度、重测信度、内部一致性以及与中文自闭症诊断访谈修订版（ADI-R）和社会反应量表（SRS）照顾者报告和自我报告形式的同时效度。还检查了 Mandarin-ADOS-G 的区分效度。
结果
Mandarin-ADOS-G 表现出良好的同评者间信度（ADOS 分类的一致性 0.91），良好的重测信度（组内相关系数 0.55-0.73）和低至高的良好内部一致性（Cronbach's alpha 0.27-0.86）。同时效度显示与 ADI-R（Pearson 相关系数 0.22-0.37）和 SRS 照顾者报告形式（Pearson 相关系数 0.15-0.23）有显著相关性。此外，所有 Mandarin-ADOS-G 域都成功地区分了自闭症个体和 TD 个体（所有 p 值<0.001）。
结论
Mandarin-ADOS-G 是一种可靠和有效的工具，可帮助普通话人群诊断 ASD。
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