Department of Speech, Language, and Hearing Science, University of Texas at Dallas, Richardson, Texas 75080, USA.
Creare LLC, Hanover, New Hampshire 03755, USA.
J Acoust Soc Am. 2023 Jan;153(1):711. doi: 10.1121/10.0017002.
A series of articles discussing advanced diagnostics that can be used to assess noise injury and associated noise-induced hearing disorders (NIHD) was developed under the umbrella of the United States Department of Defense Hearing Center of Excellence Pharmaceutical Interventions for Hearing Loss working group. The overarching goals of the current series were to provide insight into (1) well-established and more recently developed metrics that are sensitive for detection of cochlear pathology or diagnosis of NIHD, and (2) the tools that are available for characterizing individual noise hazard as personal exposure will vary based on distance to the sound source and placement of hearing protection devices. In addition to discussing the utility of advanced diagnostics in patient care settings, the current articles discuss the selection of outcomes and end points that can be considered for use in clinical trials investigating hearing loss prevention and hearing rehabilitation.
一系列讨论先进诊断方法的文章应运而生,这些方法可用于评估噪声损伤及相关的噪声性听力障碍(NIHD)。这些文章是由美国国防部听力卓越中心药物干预听力损失工作组组织编写的。本系列文章的总体目标是提供以下两方面的深入见解:(1)经过充分验证和最近开发的、对耳蜗病变检测或 NIHD 诊断具有较高敏感性的指标;(2)可用于描述个体噪声危害的工具,因为个人暴露量会因与声源的距离和听力保护装置的放置位置而有所不同。除了讨论先进诊断在患者护理环境中的实用性外,本系列文章还讨论了可用于研究听力损失预防和听力康复临床试验的结果和终点的选择。