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法医遗传学中毛发的DNA和蛋白质分析。

DNA and protein analyses of hair in forensic genetics.

作者信息

Liu Zhiyong, Simayijiang Halimureti, Wang Qiangwei, Yang Jingyi, Sun Hongyu, Wu Riga, Yan Jiangwei

机构信息

Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, People's Republic of China.

School of Forensic Medicine, Shanxi Medical University, Jinzhong, Shanxi, 030600, People's Republic of China.

出版信息

Int J Legal Med. 2023 May;137(3):613-633. doi: 10.1007/s00414-023-02955-w. Epub 2023 Feb 3.

Abstract

Hair is one of the most common pieces of biological evidence found at a crime scene and plays an essential role in forensic investigation. Hairs, especially non-follicular hairs, are usually found at various crime scenes, either by natural shedding or by forcible shedding. However, the genetic material in hairs is usually highly degraded, which makes forensic analysis difficult. As a result, the value of hair has not been fully exploited in forensic investigations and trials. In recent years, with advances in molecular biology, forensic analysis of hair has achieved remarkable strides and provided crucial clues in numerous cases. This article reviews recent developments in DNA and protein analysis of hair and attempts to provide a comprehensive solution to improve forensic hair analysis.

摘要

毛发是犯罪现场最常见的生物证据之一,在法医调查中起着至关重要的作用。毛发,尤其是无毛囊的毛发,通常通过自然脱落或强行脱落的方式出现在各种犯罪现场。然而,毛发中的遗传物质通常高度降解,这使得法医分析变得困难。因此,毛发在法医调查和审判中的价值尚未得到充分利用。近年来,随着分子生物学的发展,毛发的法医分析取得了显著进展,并在众多案件中提供了关键线索。本文综述了毛发DNA和蛋白质分析的最新进展,并试图提供一个全面的解决方案,以改进法医毛发分析。

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