Hata Tomoki, Hara Takeo, Tanizaki Keiko, Okano Miho, Takayama Osamu, Kim Yongkook, Hasegawa Junichi, Imamoto Haruhiko
Dept. of Surgery, Kaizuka City Hospital.
Gan To Kagaku Ryoho. 2022 Dec;49(13):1628-1630.
Case 1 is a 56-year-old man. During postoperative adjuvant chemotherapy for pancreatic cancer, weakness in the right upper and lower limbs appeared, and a head CT scan was performed, but no abnormal findings were noted. Diffusion- weighted MRI scan of the head showed multiple cerebral infarcts, and a diagnosis of Trousseau syndrome was made. Case 2 is an 86-year-old man. During chemotherapy for postoperative recurrence of distal bile duct carcinoma, he developed weakness in the right upper and lower limbs, and a head MRI scan was performed. Diffusion-weighted MRI showed scattered high-signal areas, and a diagnosis of Trousseau syndrome was made. Trousseau syndrome is a condition in which stroke is caused by hypercoagulability associated with malignant tumor. The initial symptoms of cerebral infarction in patients with cancer are similar to those of chemotherapy-induced adverse events and brain metastases, and therefore, a head MRI scan is recommended even if there is no obvious abnormality on head CT scan.
病例1是一名56岁男性。在胰腺癌术后辅助化疗期间，出现右上肢和下肢无力，进行了头部CT扫描，但未发现异常。头部弥散加权MRI扫描显示多发性脑梗死，诊断为特鲁索综合征。病例2是一名86岁男性。在远端胆管癌术后复发化疗期间，出现右上肢和下肢无力，进行了头部MRI扫描。弥散加权MRI显示散在高信号区，诊断为特鲁索综合征。特鲁索综合征是一种由与恶性肿瘤相关的高凝状态导致中风的疾病。癌症患者脑梗死的初始症状与化疗引起的不良事件和脑转移相似，因此，即使头部CT扫描没有明显异常，也建议进行头部MRI扫描。
