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一例特鲁索综合征：筛查、检测及并发症

A case of Trousseau syndrome: Screening, detection and complication.

作者信息

Liu Hui, Jiang Meng, Wu Nan, Liu Qingxin, Fan Xueli

机构信息

Department of Neurology, Binzhou Medical University Hospital, Binzhou, China.

Binzhou Medical University, Binzhou, China.

出版信息

Open Life Sci. 2024 Feb 8;19(1):20220824. doi: 10.1515/biol-2022-0824. eCollection 2024.

DOI:10.1515/biol-2022-0824
PMID:38465339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10921474/
Abstract

Trousseau syndrome (TS) is a malignant tumor-mediated complication of the hypercoagulable state with an unknown etiology. Laboratory testing results in patients with TS have indicated elevated D-dimer levels. The imaging analysis in patients who had undergone stroke has shown the presence of several cerebral infarction lesions in multiple regions. Since patients have had malignant tumors for a long time when they suffer from a secondary stroke, the optimum time for radical tumor treatment is usually missed. This study reports a case to improve the early screening and detection of TS and reduce the risk of recurrence of cerebral infarction.

摘要

特鲁索综合征（TS）是一种病因不明的恶性肿瘤介导的高凝状态并发症。TS患者的实验室检测结果显示D-二聚体水平升高。中风患者的影像学分析表明，多个区域存在多处脑梗死病灶。由于患者在发生继发性中风时已患有恶性肿瘤很长时间，通常会错过根治肿瘤的最佳时机。本研究报告了1例病例，以提高TS的早期筛查和检测，并降低脑梗死复发风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/9a6ba133d159/j_biol-2022-0824-fig006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/70b6786207a5/j_biol-2022-0824-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/d6c0abdfbdfa/j_biol-2022-0824-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/6e3240d7fb49/j_biol-2022-0824-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/5d0c6d3c4320/j_biol-2022-0824-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/721d45325dd0/j_biol-2022-0824-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/9a6ba133d159/j_biol-2022-0824-fig006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/70b6786207a5/j_biol-2022-0824-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/d6c0abdfbdfa/j_biol-2022-0824-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/6e3240d7fb49/j_biol-2022-0824-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/5d0c6d3c4320/j_biol-2022-0824-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/721d45325dd0/j_biol-2022-0824-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f98/10921474/9a6ba133d159/j_biol-2022-0824-fig006.jpg

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本文引用的文献

1
Clinical analysis of twenty-one cases of acute ischemic stroke related to Trousseau syndrome.二十一例 Trousseau 综合征相关急性缺血性脑卒中的临床分析。
Neurol Sci. 2024 Apr;45(4):1537-1547. doi: 10.1007/s10072-023-07180-2. Epub 2023 Nov 13.
2
Stroke as initial manifestation of non-small cell lung cancer with Trousseau syndrome.以 Trousseau 综合征为首发表现的非小细胞肺癌合并脑卒中。
BMC Cancer. 2023 Nov 10;23(1):1096. doi: 10.1186/s12885-023-11627-2.
3
Trousseau Syndrome in a Case of Extramammary Paget's Disease.一例乳腺外佩吉特病合并特鲁索综合征
Acta Derm Venereol. 2023 Sep 27;103:adv9405. doi: 10.2340/actadv.v103.9405.
4
A case report of Trousseau syndrome.特鲁索（氏）综合征病例报告。
Medicine (Baltimore). 2023 Jul 28;102(30):e34449. doi: 10.1097/MD.0000000000034449.
5
[Two Cases of Trousseau Syndrome during Chemotherapy].[化疗期间的两例特鲁索综合征]
Gan To Kagaku Ryoho. 2022 Dec;49(13):1628-1630.
6
A case of pancreatic head cancer with Trousseau's syndrome treated with radical resection and anticoagulant therapy.1例胰头癌伴特鲁索综合征行根治性切除及抗凝治疗的病例。
Surg Case Rep. 2023 Jan 12;9(1):6. doi: 10.1186/s40792-023-01585-z.
7
Pancreatic cancer with multiple liver metastasis complicating multi-organ infarcts from marantic endocarditis and Trousseau's syndrome.胰腺癌伴多发肝转移，并发消耗性心内膜炎和特鲁索综合征所致多器官梗死。
Clin Med (Lond). 2022 Jul;22(Suppl 4):29-30. doi: 10.7861/clinmed.22-4-s29.
8
Recurrent Strokes as the First Presentation of Occult Pancreatic Cancer; Trousseau Syndrome: A Case Report.复发性中风作为隐匿性胰腺癌的首发表现；特鲁索综合征：一例报告
Case Rep Oncol. 2021 Dec 10;14(3):1741-1747. doi: 10.1159/000520759. eCollection 2021 Sep-Dec.
9
Trousseau Syndrome Related Cerebral Infarction: Clinical Manifestations, Laboratory Findings and Radiological Features.特鲁索综合征相关脑梗死：临床表现、实验室检查及影像学特征。
J Stroke Cerebrovasc Dis. 2020 Sep;29(9):104891. doi: 10.1016/j.jstrokecerebrovasdis.2020.104891. Epub 2020 Jun 30.
10
Trousseau syndrome.
Cleve Clin J Med. 2020 Apr;87(4):199-200. doi: 10.3949/ccjm.87a.19086.