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Editorial: Body fluid biomarkers in neurodegenerative studies: Novel insights into pathophysiology to support clinical practice and drug development.社论:神经退行性疾病研究中的体液生物标志物:对病理生理学的新见解,以支持临床实践和药物开发。
Front Neurol. 2023 Jan 17;14:1103116. doi: 10.3389/fneur.2023.1103116. eCollection 2023.
2
Cerebrospinal fluid biomarkers in Alzheimer's and Parkinson's diseases-From pathophysiology to clinical practice.阿尔茨海默病和帕金森病中的脑脊液生物标志物——从病理生理学到临床实践
Mov Disord. 2016 Jun;31(6):836-47. doi: 10.1002/mds.26656. Epub 2016 May 4.
3
Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders.神经退行性变的途径:来自阿尔茨海默病、帕金森病及相关疾病全基因组关联研究的机制洞察
Am J Neurodegener Dis. 2013 Sep 18;2(3):145-75.
4
The Emerging Role of Circular RNAs in Alzheimer's Disease and Parkinson's Disease.环状RNA在阿尔茨海默病和帕金森病中的新兴作用
Front Aging Neurosci. 2021 Jul 12;13:691512. doi: 10.3389/fnagi.2021.691512. eCollection 2021.
5
Cerebrospinal Fluid Biomarkers for Target Engagement and Efficacy in Clinical Trials for Alzheimer's and Parkinson's Diseases.用于阿尔茨海默病和帕金森病临床试验中靶点验证及疗效评估的脑脊液生物标志物
Front Neurol Neurosci. 2016;39:117-23. doi: 10.1159/000445452. Epub 2016 Jul 26.
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OMICS. 2016 Nov;20(11):645-661. doi: 10.1089/omi.2016.0106.
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The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases.BIOMARKAPD的中央生物样本库和虚拟生物样本库:神经退行性疾病研究资源
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Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease.检测呼出气体中的化合物以诊断阿尔茨海默病和帕金森病。
PLoS One. 2015 Jul 13;10(7):e0132227. doi: 10.1371/journal.pone.0132227. eCollection 2015.
10
The Role of Salivary Biomarkers in the Early Diagnosis of Alzheimer's Disease and Parkinson's Disease.唾液生物标志物在阿尔茨海默病和帕金森病早期诊断中的作用
Diagnostics (Basel). 2021 Feb 22;11(2):371. doi: 10.3390/diagnostics11020371.

本文引用的文献

1
Safety and Efficacy of Monoclonal Antibodies for Alzheimer's Disease: A Systematic Review and Meta-Analysis of Published and Unpublished Clinical Trials.用于阿尔茨海默病的单克隆抗体的安全性和疗效:已发表和未发表临床试验的系统评价和荟萃分析。
J Alzheimers Dis. 2022;87(1):101-129. doi: 10.3233/JAD-220046.
2
Synuclein in neurodegeneration.神经退行性变中的突触核蛋白。
Adv Clin Chem. 2021;103:97-134. doi: 10.1016/bs.acc.2020.08.007. Epub 2020 Oct 20.
3
A multicentre validation study of the diagnostic value of plasma neurofilament light.血浆神经丝轻链的诊断价值的多中心验证研究。
Nat Commun. 2021 Jun 7;12(1):3400. doi: 10.1038/s41467-021-23620-z.
4
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease.血浆生物标志物在阿尔茨海默病中的诊断和预后能力。
Alzheimers Dement. 2021 Jul;17(7):1145-1156. doi: 10.1002/alz.12283. Epub 2021 Jan 25.
5
The global burden of neurological disorders.神经疾病的全球负担。
Lancet Neurol. 2019 May;18(5):418-419. doi: 10.1016/S1474-4422(19)30029-8. Epub 2019 Mar 14.
6
Decreased Cerebrospinal Fluid Aβ42 in Patients with Idiopathic Parkinson's Disease and White Matter Lesions.特发性帕金森病伴白质病变患者脑脊液 Aβ42 减少。
J Parkinsons Dis. 2019;9(2):361-367. doi: 10.3233/JPD-181486.
7
Early Cognitive Domain Deficits in Patients with Aneurysmal Subarachnoid Hemorrhage Correlate with Functional Status.动脉瘤性蛛网膜下腔出血患者早期认知领域缺陷与功能状态相关。
Acta Neurochir Suppl. 2016;122:129-32. doi: 10.1007/978-3-319-22533-3_26.
8
A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes.一个由九种脑脊液生物标志物组成的小组可能可以识别出具有非典型帕金森综合征的患者。
J Neurol Neurosurg Psychiatry. 2015 Nov;86(11):1240-7. doi: 10.1136/jnnp-2014-309562. Epub 2015 Jan 14.
9
Cerebrospinal fluid biomarker candidates for parkinsonian disorders.帕金森病相关的脑脊液生物标志物候选物。
Front Neurol. 2013 Jan 21;3:187. doi: 10.3389/fneur.2012.00187. eCollection 2012.

Editorial: Body fluid biomarkers in neurodegenerative studies: Novel insights into pathophysiology to support clinical practice and drug development.

作者信息

Bougea Anastasia, Svenningsson Per, Markaki Ioanna, Hye Abdul, Mondello Stefania

机构信息

First Department of Neurology, Eginition Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

出版信息

Front Neurol. 2023 Jan 17;14:1103116. doi: 10.3389/fneur.2023.1103116. eCollection 2023.

DOI:10.3389/fneur.2023.1103116
PMID:36733314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9887318/
Abstract
摘要