Lu Jin-Xian, Song Quan-Mei, Zhang Xue-Cheng, Lu Yong-Hui, Wang Jing-Yu, Jia Hong-Ling, Zhang Yong-Chen
School of Acupuncture-Moxibustion and Massage, Shandong University of Traditional Chinese Medicine, Jinan 250014, China.
Key Laboratory of Chinese Internal Medicine, Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700.
Zhen Ci Yan Jiu. 2023 Jan 25;48(1):44-52. doi: 10.13702/j.1000-0607.20221110.
To explore the rules of acupoints selection of acupuncture and moxibustion in the treatment of allergic rhinitis (AR) by using data mining technology, as well as to compare the efficacy of different acupoints selection methods.
Papers about acupuncture and moxibustion for treating AR published from January 2002 to August 2022 was retrieved from Chinese and English databases including CNKI, Wanfang, VIP, SinoMed and PubMed by using keywords of "acupuncture", "moxibustion" and "allergic rhinitis". According to the inclusion and exclusion criteria, the collected literature was screened to establish the AR database. Frequency statistic analysis was conducted for detecting high-frequency acupoints and specific acupoints frequency, and the curative effects of different acupoints selection methods were compared. SPSS26.0 software was used for factor analysis, cluster analysis and QUEST decision tree model identification.
A total of 289 papers were included, with 384 acupuncture prescriptions extracted. A total of 99 acupoints were involved with the application frequency of 2 430 times. Among them, the application frequency of Yingxiang (LI20) is the highest (296 times, 12.18%), followed by Yintang (GV24) and Hegu (LI4), etc. The main invloved meridians are the Bladder Meridian of Foot-Taiyang, the Large Intestine Meridian of Hand-Yangming and the Governor Vessel. The involved specific acupoints with the highest frequency of application is the crossing acupoints. Nine common factors of acupoints combinations units were extracted by factor analysis, and two cluster prescriptions of acupoints combinations correlation were obtained by cluster analysis. Three decision paths of simplified acupoints selection were simulated by the decision tree, with LI20 as the dependent variable.
In the treatment of AR with acupuncture and moxibustion, the regularities and characteristics of acupoints selection are as follows: 1) often selecting local acupoints and acupoint combinations along meridians, 2) focusing on combination of dispelling pathogenic factors with strengthening vital energy, 3) advocating diversification of acupoint matching methods. The combination of factor analysis, cluster analysis and QUEST decision tree application provides three directions for clinical acupoints selection of AR.
运用数据挖掘技术探讨针灸治疗变应性鼻炎(AR)的选穴规律,并比较不同选穴方法的疗效。
采用“针灸”“艾灸”“变应性鼻炎”等关键词,从中国知网(CNKI)、万方、维普、中国生物医学文献数据库(SinoMed)及PubMed等中英文数据库中检索2002年1月至2022年8月发表的关于针灸治疗AR的文献。按照纳入与排除标准,对收集的文献进行筛选,建立AR数据库。进行频次统计分析以检测高频穴位及特定穴位频次,并比较不同选穴方法的疗效。运用SPSS26.0软件进行因子分析、聚类分析及QUEST决策树模型识别。
共纳入289篇文献,提取384个针灸处方。共涉及99个穴位,应用频次为2430次。其中,迎香(LI20)应用频次最高(296次,12.18%),其次为印堂(GV24)、合谷(LI4)等。主要涉及的经脉为足太阳膀胱经、手阳明大肠经及督脉。应用频次最高的特定穴位为交会穴。通过因子分析提取出9个穴位组合单元的共同因子,通过聚类分析得到2个穴位组合相关性聚类处方类。以LI20为因变量,通过决策树模拟出3条简化选穴决策路径。
针灸治疗AR的选穴规律及特点如下:1)常选取局部穴位及循经穴位配伍;2)注重祛邪与扶正相结合;3)提倡穴位配伍方法多样化。因子分析、聚类分析及QUEST决策树的联合应用为AR临床选穴提供了3个方向。