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[氟桂利嗪治疗癫痫。对现有抗癫痫药物治疗耐药患者进行4个月补充治疗的评估]

[Flunarizine in epilepsy. Evaluation of a 4-month supplementary treatment in patients resistant to treatment with existing antiepileptics].

作者信息

Sorel L

机构信息

Centre Neurologique William Lennox, Ottignies.

出版信息

Acta Neurol Belg. 1987 May-Jul;87(3):140-7.

PMID:3673491
Abstract

Twenty patients affected with a form of epilepsy resistant to treatment received 10 to 20 mg of flunarizine per day in addition to the anti-epileptic medication. The majority of the patients suffered from partial epilepsy with or without secondary generalization. The flunarizine treatment was evaluated after four months. On the whole, flunarizine was well tolerated. The number of attacks was reduced by 50% or more in half the patients.

摘要

20名患有难治性癫痫的患者在服用抗癫痫药物的基础上,每天加服10至20毫克氟桂利嗪。大多数患者患有伴有或不伴有继发性全身性发作的部分性癫痫。四个月后对氟桂利嗪治疗效果进行评估。总体而言,氟桂利嗪耐受性良好。半数患者的发作次数减少了50%或更多。

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