Department of Urology, Radboud University Medical Centre Amalia Children's Hospital, Nijmegen, The Netherlands.
Department of Medical Psychology and Social Work, Wilhelmina Children's Hospital Utrecht, Utrecht, The Netherlands.
PLoS One. 2023 Feb 3;18(2):e0275958. doi: 10.1371/journal.pone.0275958. eCollection 2023.
Wearable alarm systems are frequently used tools added to urotherapy for children with both daytime and nighttime urinary incontinence. For functional daytime incontinence (DUI) specifically, the effect of alarm interventions has not been systematically reviewed. This study systematically evaluates, summarizes, reviews, and analyzes existing evidence about the effect of wearable alarm systems in urotherapy for children with functional DUI.
We completed a comprehensive literature search in August 2022 using MEDLINE/PUBMED, EMBASE, PsycINFO, Cochrane Library, Web of Science, Google Scholar, conference abstracts, and citation tracking. Clinical controlled trials at controlled-trials.com and clinicaltrials.gov were consulted, as was the National health Service Center For Reviews And Dissemination. Eligible studies including the use of noninvasive wearable alarm systems as (part of) treatment for functional DUI in children were included. The main outcome was continence after treatment. Three independent reviewers extracted data. Risk of bias was assessed using Cochrane and National Heart, Lung and Blood Institute quality assessment tools.
A total of 10 studies out of 1,382 records were included. Meta-analysis revealed a nonsignificant risk ratio of 1.4 (95% CI: 0.8-2.6) for the use of alarm systems. Urotherapy with alarm systems resulted in a 48% (95% CI: 33-62%) continence rate after treatment.
Alarm systems might be helpful as part of urotherapy for functional DUI in select cases. Adherence is problematic, and the optimal duration of the use of alarm systems is to be determined. Overall, the risk of bias was high in all studies.
可穿戴报警系统常用于日间和夜间遗尿的儿童的尿疗中。具体来说,对于功能性日间遗尿(DUI),报警干预的效果尚未得到系统评价。本研究系统地评估、总结、回顾和分析了可穿戴报警系统在儿童功能性 DUI 尿疗中的现有证据。
我们于 2022 年 8 月使用 MEDLINE/PUBMED、EMBASE、PsycINFO、Cochrane 图书馆、Web of Science、Google Scholar、会议摘要和引文追踪进行了全面的文献检索。还咨询了 controlled-trials.com 和 clinicaltrials.gov 的临床对照试验以及英国国家卫生服务中心的审查和传播中心。纳入了包括使用非侵入性可穿戴报警系统作为(部分)治疗儿童功能性 DUI 的研究。主要结局是治疗后的尿控情况。三名独立的审查员提取数据。使用 Cochrane 和美国国立心肺血液研究所的质量评估工具评估了偏倚风险。
在 1382 条记录中,共有 10 项研究符合纳入标准。Meta 分析显示,使用报警系统的风险比为 1.4(95%可信区间:0.8-2.6),无显著意义。报警系统联合尿疗可使治疗后尿控率达到 48%(95%可信区间:33-62%)。
在某些情况下,报警系统可能有助于作为尿疗的一部分治疗功能性 DUI。但患者的依从性存在问题,且报警系统的最佳使用时间尚待确定。总体而言,所有研究的偏倚风险都很高。