Yang Zhaoxu, Xing Dong, Dong Zhijie, Wei Jingchao, Zhang Long, Gao Shangju, Li Wenyi
Altern Ther Health Med. 2023 Apr;29(3):207-211.
With the rapidly aging population globally, osteoporosis (OP) has become a major public health problem, and fracture is a common complication of OP. Older adults, especially postmenopausal women, have a higher incidence of OP.
The study intended to analyze the clinical information, epidemiological characteristics, treatments, and follow-up results of patients with osteoporotic fractures (OPFs) in adults over 65 years old, to provide data support for the prevention, treatment, and use of OPF focus groups in clinical practice.
The research team performed a retrospective analysis using electronic medical records and related imaging data of patients.
The study took place at Hebei General Hospital in Hebei, China.
Participants were 387 patients over 65 years old with osteoporotic fractures who had been admitted to the hospital between July 2012 and July 2018.
The research team recorded participants' ages, genders, fracture causes, and fracture sites. The team performed a follow-up analysis on refractures, treatment with anti-osteoporotic drugs, exercise, and survival status within the 3 years after surgery.
The study's male-to-female ratio was 1:3.1, and the rate of osteoporotic fracture for females was significantly higher than that of males. The mean age of participants with fractures was 75.6 ± 8.5 years, and most fractures occurred in participants 78 to 85 years old. Of the 387 participants, 169 participants had hip fractures (43.67%); 98 had vertebral compression fractures (25.32%); 51 had distal radius and ulna fractures (13.18%); 42 had proximal humerus fractures (10.85%); and 27 had other fractures (6.98%). The number of women with fractures at each site was greater than the number of men, but the differences weren't statistically significant (P > .05). The main causes of injury were falls (71.58%), and the main place of the occurrence of injury was at home (65.6%). Of the 387 participants, 346 had surgical treatment (89.41%), and the effective rate of surgical treatment was 99.42%. Three years after surgery, the research team followed up with 235 participants, for a follow-up rate of 60.72%. Within the 3 years of the follow-up period, 61 participants had refractures (25.63%), 29 received treatment with regular anti-osteoporotic drugs (12.34%), 36 exercised twice or more a week (15.32%), and 32 had died for various reasons (13.62%).
The study preliminarily described the epidemiological characteristics of 387 osteoporotic fractures in adults over 65 years old. More women had fractures than men; the hip was the most common fracture site, and falls were the main cause of injury. Most of the fractures occurred in the place of residence, and the refracture rate was 25.96% at three years after surgery.
随着全球人口迅速老龄化，骨质疏松症（OP）已成为一个主要的公共卫生问题，骨折是OP的常见并发症。老年人，尤其是绝经后女性，OP的发病率更高。
本研究旨在分析65岁以上成人骨质疏松性骨折（OPF）患者的临床信息、流行病学特征、治疗方法及随访结果，为临床实践中OPF重点人群的预防、治疗及利用提供数据支持。
研究团队使用患者的电子病历和相关影像数据进行回顾性分析。
本研究在中国河北河北医科大学第一医院进行。
参与者为2012年7月至2018年7月期间入院的387例65岁以上骨质疏松性骨折患者。
研究团队记录参与者的年龄、性别、骨折原因和骨折部位。团队对术后3年内的再骨折、抗骨质疏松药物治疗、运动及生存状况进行了随访分析。
本研究的男女比例为1:3.1，女性骨质疏松性骨折发生率显著高于男性。骨折参与者的平均年龄为75.6±8.5岁，大多数骨折发生在78至85岁的参与者中。在387名参与者中，169名参与者发生髋部骨折（43.67%）；98名发生椎体压缩性骨折（25.32%）；51名发生桡骨远端和尺骨骨折（13.18%）；42名发生肱骨近端骨折（10.85%）；27名发生其他骨折（6.98%）。各部位骨折的女性人数均多于男性，但差异无统计学意义（P>.05）。主要损伤原因是跌倒（71.58%），主要损伤发生地点是在家中（65.6%）。在387名参与者中，346名接受了手术治疗（89.41%），手术治疗有效率为99.42%。术后3年，研究团队对235名参与者进行了随访，随访率为60.72%。在随访期的3年内，61名参与者发生再骨折（25.63%），29名接受常规抗骨质疏松药物治疗（12.34%），36名每周锻炼两次或更多（15.32%），32名因各种原因死亡（13.62%）。
本研究初步描述了387例65岁以上成人骨质疏松性骨折的流行病学特征。骨折女性多于男性；髋部是最常见的骨折部位，跌倒是主要损伤原因。大多数骨折发生在居住场所，术后3年再骨折率为25.96%。
