紧张性木僵期间迟发性运动障碍消失。

Disappearance of tardive dyskinesia during catatonic stupor.

作者信息

Assmann V C, van Woerkom T C

机构信息

Department of Neuropsychiatry, Psychiatric Centre Rosenburg, The Hague, The Netherlands.

出版信息

Acta Psychiatr Scand. 1987 Aug;76(2):217-8. doi: 10.1111/j.1600-0447.1987.tb02887.x.

DOI:10.1111/j.1600-0447.1987.tb02887.x

PMID:3673646

Abstract

A 61-year-old man diagnosed as having catatonic schizophrenia was treated with neuroleptics for many years. From 1983 he showed tardive dyskinesia on trunk and limbs as well as orofacial dyskinesia. In September 1985 he displayed a catatonic stupor several times. With the outbreak of the stupor the dyskinesia disappeared and vice varsa. This finding induces the hypothesis that the dopaminergic system is suppressed during catatonic stupor in such a way that tardive dyskinesia is no longer visible.

摘要

一名61岁被诊断为紧张型精神分裂症的男子接受抗精神病药物治疗多年。自1983年起，他出现了躯干和四肢的迟发性运动障碍以及口面部运动障碍。1985年9月，他多次出现紧张性木僵。随着木僵的发作，运动障碍消失，反之亦然。这一发现引发了这样一种假说，即在紧张性木僵期间多巴胺能系统受到抑制，以至于迟发性运动障碍不再可见。