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年龄和病程作为慢性精神分裂症患者脑室脑比率(VBR)大小的预测因素。一项逐步回归分析研究。

Age and duration of illness as predictors of ventricular brain ratio (VBR) size in chronic schizophrenic patients. A stepwise regression analysis study.

作者信息

Rossi A, Stratta P, Casacchia M, D'Albenzio L, Schiazza G, De Donatis M

机构信息

Cattedra di Clinica Psichiatrica, Ospedale S. Maria Collemaggio, L'Aquila, Italy.

出版信息

Acta Psychiatr Scand. 1987 Sep;76(3):256-60. doi: 10.1111/j.1600-0447.1987.tb02893.x.

DOI:10.1111/j.1600-0447.1987.tb02893.x
PMID:3673652
Abstract

The CT scans of 18 chronic schizophrenic patients and 17 controls were evaluated for Ventricular Brain Ratio (VBR) size. A trend for the patient group to have larger VBR than controls was present but did not reach statistical significance at the 5% level. Age was found to be an important correlate of VBR within the patient group but not among controls. In a stepwise multiple-regression model age, among other independent variables, can account for 47% of VBR variance in schizophrenic patients. Linear regression analysis did not reveal significant association between VBR and age in control subjects.

摘要

对18名慢性精神分裂症患者和17名对照者的CT扫描进行了脑室脑比率(VBR)大小评估。患者组的VBR有大于对照组的趋势,但在5%水平未达到统计学显著性。发现年龄是患者组中VBR的一个重要相关因素,但在对照组中并非如此。在逐步多元回归模型中,年龄以及其他自变量可解释精神分裂症患者VBR变异的47%。线性回归分析未显示对照组中VBR与年龄之间存在显著关联。

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The ageing brain, neuroleptic drugs and the enigma of schizophrenia.衰老的大脑、抗精神病药物与精神分裂症之谜
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