Department of Prosthodontics, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Department of Restorative Dental Sciences, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Photodiagnosis Photodyn Ther. 2023 Jun;42:103320. doi: 10.1016/j.pdpdt.2023.103320. Epub 2023 Feb 1.
The objective of this short-term follow-up study was to evaluate the influence of antimicrobial photodynamic therapy (aPDT) as an adjuvant to mechanical debridement (MD) in reducing soft-tissue inflammation and subgingival yeasts colonization (SYC) in patients with peri‑implant mucositis (PiM).
Individuals diagnosed with PiM were included. Demographic data was collected using a questionnaire. Peri-implant plaque index (PI), bleeding index (BI), probing depth (PD), crestal bone levels and SYC were measured at baseline. Therapeutically, these individuals were divided into test and control groups. In the control-group patients underwent MD and in the test-group patients underwent MD with adjunct single session of aPDT. Clinical peri‑implant parameters and SYC were reassessed after 12-weeks. Correlation between age, gender and duration of implants with SYC and clinical peri‑implant status was assessed using logistic regression models. P < 0.05 was selected as an indicator of statistical significance.
The test and control-groups comprised of 24 and 23 individuals, respectively. In the test and control groups, toothbrushing twice daily was reported by 7 (29.2%) and 5 (21.7%) individuals, respectively. None of the individuals had ever used a dental floss. At baseline, there was no difference in peri‑implant PI, BI, PD and CBL in the test and control groups. At follow-up, peri‑implant PI (P < 0.01), BI (P < 0.01) and PD (P < 0.01) were significantly higher in the control compared with the test-group. At baseline, SYC in the test and control groups were 1865.3 ± 403.4 CFU/ml and 1963.7 ± 512.4 CFU/ml, respectively. At 90 days' follow-up, SYC in the test and control groups were 1472 ± 202.7 and 1538.4 ± 331.7 CFU/ml, respectively. There was no significant difference in SYC in both groups when baseline values were compared with 90 days' follow-up.
One session of aPDT after MC with adjunct aPDT is effective in reducing soft tissue inflammation but not SYC in patients with PiM.
本短期随访研究旨在评估抗菌光动力疗法（aPDT）作为机械清创术（MD）辅助治疗对减轻种植体周围黏膜炎（PiM）患者软组织炎症和龈下酵母菌定植（SYC）的影响。
纳入诊断为 PiM 的个体。使用问卷收集人口统计学数据。基线时测量种植体周围菌斑指数（PI）、出血指数（BI）、探诊深度（PD）、牙槽骨嵴水平和 SYC。治疗上，这些个体分为试验组和对照组。对照组患者接受 MD，试验组患者接受 MD 联合单次 aPDT。12 周后重新评估临床种植体参数和 SYC。使用逻辑回归模型评估年龄、性别和种植体植入时间与 SYC 和临床种植体状况之间的相关性。选择 P<0.05 作为统计学意义的指标。
试验组和对照组分别包括 24 名和 23 名个体。在试验组和对照组中，分别有 7（29.2%）和 5（21.7%）名个体报告每天刷牙两次。没有个体使用过牙线。基线时，试验组和对照组的种植体 PI、BI、PD 和 CBL 无差异。随访时，对照组的种植体 PI（P<0.01）、BI（P<0.01）和 PD（P<0.01）均明显高于试验组。基线时，试验组和对照组的 SYC 分别为 1865.3±403.4 CFU/ml 和 1963.7±512.4 CFU/ml。90 天随访时，试验组和对照组的 SYC 分别为 1472±202.7 和 1538.4±331.7 CFU/ml。与基线相比，两组 90 天随访时 SYC 无显著差异。
MC 后单次 aPDT 联合 aPDT 治疗可有效减轻 PiM 患者的软组织炎症，但不能减轻 SYC。
