Arenas-Jiménez J J, García-Garrigós E, Ureña Vacas A, Sirera Matilla M, Feliu Rey E
Departamento de Patología y Cirugía, Hospital General Universitario Dr. Balmis, Departamento de Patología y Cirugía, Universidad Miguel Hernández, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.
Servicio de Radiología, Hospital General Universitario Dr. Balmis, Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.
Radiologia (Engl Ed). 2022 Dec;64 Suppl 3:240-249. doi: 10.1016/j.rxeng.2022.08.002.
Organizing pneumonia is a nonspecific pathologic pattern of response to lung damage. It can be idiopathic, or it can occur secondary to various medical processes, most commonly infections, connective tissue disease, and pharmacological toxicity. Although there is no strict definition of the pattern of organising pneumonia as in other idiopathic interstitial pneumonias, the characteristic pattern of this disease could be considered to include patchy consolidations and ground-glass opacities in the peribronchial and subpleural areas of both lungs. Moreover, studies of the course of the disease show that these lesions respond to treatment with corticoids, migrate with or without treatment, and tend to recur when treatment is decreased or withdrawn. Other manifestations of organising pneumonia include nodules of different sizes and shapes, solitary masses, nodules with the reverse halo sign, a perilobular pattern, and parenchymal bands.
机化性肺炎是对肺损伤的一种非特异性病理反应模式。它可以是特发性的，也可继发于各种医疗过程，最常见的是感染、结缔组织病和药物毒性。尽管与其他特发性间质性肺炎不同，机化性肺炎的模式没有严格定义，但该病的特征性模式可认为包括两肺支气管周围和胸膜下区域的斑片状实变及磨玻璃影。此外，对该病病程的研究表明，这些病变对皮质类固醇治疗有反应，无论治疗与否都会迁移，且在治疗减量或停药时往往会复发。机化性肺炎的其他表现包括不同大小和形状的结节、孤立性肿块、具有反晕征的结节、小叶周围模式和实质带。
