Cheng T, Wang F, Denisova K, Barmettler A
Department of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States.
Department of Ophthalmology and Visual Sciences, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, United States.
Arch Soc Esp Oftalmol (Engl Ed). 2023 Apr;98(4):199-205. doi: 10.1016/j.oftale.2023.02.002. Epub 2023 Feb 2.
Normative exophthalmometry values have been established in Caucasians, Asians, and Black individuals. While prior studies have examined periocular measurements in different racial and ethnic groups, this study is the first to establish a set of normative exophthalmometry values in a Hispanic population in New York City.
This prospective, cross-sectional cohort study was IRB approved and HIPAA compliant. Adult patients self-identifying as Hispanic were included. The degree of ocular prominence (exophthalmometry value, EV) and the inter-orbital distance (Hertel's base, IOD) was obtained by Hertel exophthalmometry. Differences in EV between sexes were evaluated using two sample t-tests. Multivariable linear regression was utilized to determine the effect of age, sex, and body mass index (BMI) on EV.
Of the 277 Hispanic individuals included, 189 (68.2%) were female and the mean age was 63.0 years (SD = 15.0). The mean Hertel's base and mean EV for all participants was 92.0 mm (SD = 4.1) and 16.7 mm (SD = 2.4), respectively. Average exophthalmometry values for men were significantly higher than women's (17.6 mm and 16.2 mm, respectively, p ≤ 0.001). Higher EVs were positively associated with male gender (ß = -1.60, p < 0.0001) and BMI (ß = 0.084, p = 0.001), but not age.
The mean EV in Hispanic individuals is 16.7 mm, higher than that reported for most Caucasians and Asians, but less than that of Black individuals. Higher EV is significantly associated with male sex and increased BMI. This study is the first to create a set of normative exophthalmometry values in a Hispanic population, which may serve as a valuable tool for clinicians to reference when diagnosing and monitoring orbital disease.
已确定白种人、亚洲人和黑人的正常眼球突出度测量值。虽然先前的研究已经对不同种族和族裔群体的眼周测量进行了研究，但本研究首次在纽约市的西班牙裔人群中建立了一套正常眼球突出度测量值。
这项前瞻性横断面队列研究经机构审查委员会（IRB）批准并符合健康保险流通与责任法案（HIPAA）。纳入自我认定为西班牙裔的成年患者。通过Hertel眼球突出度测量法获得眼球突出程度（眼球突出度测量值，EV）和眶间距离（Hertel基线，IOD）。使用两样本t检验评估性别间EV的差异。采用多变量线性回归来确定年龄、性别和体重指数（BMI）对EV的影响。
纳入的277名西班牙裔个体中，189名（68.2%）为女性，平均年龄为63.0岁（标准差=15.0）。所有参与者的平均Hertel基线和平均EV分别为92.0毫米（标准差=4.1）和16.7毫米（标准差=2.4）。男性的平均眼球突出度测量值显著高于女性（分别为17.6毫米和16.2毫米，p≤0.001）。较高的EV与男性性别（β=-1.60，p<0.0001）和BMI（β=0.084，p=0.001）呈正相关，但与年龄无关。
西班牙裔个体的平均EV为16.7毫米，高于大多数白种人和亚洲人报告的数值，但低于黑人个体。较高的EV与男性性别和BMI增加显著相关。本研究首次在西班牙裔人群中建立了一套正常眼球突出度测量值，这可能为临床医生在诊断和监测眼眶疾病时提供有价值的参考工具。
