用替莫泊芬钠进行光动力疗法治疗恶性中央气道狭窄的激光剂量研究。
A study of laser dose in photodynamic therapy with talaporfin sodium for malignant central airway stenosis.
作者信息
Tsuchida Takaaki, Matsumoto Yuji, Imabayashi Tatsuya, Uchimura Keigo
机构信息
Respiratory Endoscopy Division, Department of Endoscopy, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
Respiratory Endoscopy Division, Department of Endoscopy, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
出版信息
Photodiagnosis Photodyn Ther. 2023 Mar;41:103315. doi: 10.1016/j.pdpdt.2023.103315. Epub 2023 Feb 3.
Photodynamic therapy (PDT) has been shown to be effective and safe in the treatment of malignant central airway stenosis. However, the laser dose for talaporfin PDT is unclear. We herein review cases where talaporfin PDT was used to treat malignant central airway stenosis. A total of 17 lesions were treated with talaporfin PDT at laser doses of 50-150 J/cm. Improvement of airway stenosis was observed in all cases except for 1 lesion treated with a dose of 50 J/cm. The results show that talaporfin PDT with 100 J/cm of laser dose is a feasible treatment for malignant central airway stenosis. (This is a secondary publication from the Journal of Japan Society for Laser Surgery and Medicine 2022; 43(1): 9-12.).
光动力疗法（PDT）已被证明在治疗恶性中央气道狭窄方面有效且安全。然而，他拉泊芬光动力疗法的激光剂量尚不清楚。我们在此回顾了使用他拉泊芬光动力疗法治疗恶性中央气道狭窄的病例。共有17个病变接受了他拉泊芬光动力疗法治疗，激光剂量为50 - 150 J/cm。除1个接受50 J/cm剂量治疗的病变外，所有病例均观察到气道狭窄有所改善。结果表明，激光剂量为100 J/cm的他拉泊芬光动力疗法是治疗恶性中央气道狭窄的一种可行方法。（这是日本激光外科学会杂志2022年的二次发表；43(1): 9 - 12。）
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