Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Catholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Korean J Intern Med. 2023 Mar;38(2):157-166. doi: 10.3904/kjim.2022.271. Epub 2023 Feb 6.
The prevalence of heart failure with preserved ejection fraction (HFpEF) has increased in recent decades. In particular, obesity-related HFpEF is a distinct and frequently encountered phenotype; however, its diagnosis is complex. Furthermore, the management of obesity-related HFpEF has not been established despite the introduction of promising drugs. This review summarizes the diagnostic challenges, pathophysiology, and therapeutic options for obesity-related HFpEF.
近年来，射血分数保留的心力衰竭（HFpEF）的患病率有所增加。特别是，肥胖相关性 HFpEF 是一种独特且常见的表型；然而，其诊断较为复杂。此外，尽管出现了有前途的药物，但肥胖相关性 HFpEF 的治疗方法尚未确定。本文总结了肥胖相关性 HFpEF 的诊断挑战、病理生理学和治疗选择。
