Song Jimin, Kang Wonil, Ohn Suk Hoon, Jung Kwang-Ik, Bashir Shahid, Yoo Woo-Kyoung
Department of Physical Medicine and Rehabilitation, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Neuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia.
Brain Neurorehabil. 2020 Nov 24;14(1):e1. doi: 10.12786/bn.2021.14.e1. eCollection 2021 Mar.
Lance-Adams syndrome (LAS) is a rare neurological disorder that may occur after cardiopulmonary resuscitation. The LAS is usually caused by hypoxic changes. Neuroimaging studies show that the brain pathology of LAS patients is not uniform, and the pathophysiology of the myoclonus can vary from patient to patient. Our case study contributes to this etiological heterogeneity by neuroimaging and transcranial magnetic stimulation (TMS). In patients with rare brain conditions such as LAS, a combination of brain stimulation methods, such as TMS, and diffusion tensor imaging can provide insights into this condition's pathophysiology. These insights can facilitate the development of more effective therapies.
兰斯-亚当斯综合征(LAS)是一种罕见的神经系统疾病,可能发生在心肺复苏后。LAS通常由缺氧变化引起。神经影像学研究表明,LAS患者的脑部病理并不一致,肌阵挛的病理生理学在不同患者之间也可能有所不同。我们的病例研究通过神经影像学和经颅磁刺激(TMS)为这种病因异质性提供了依据。在LAS等罕见脑部疾病的患者中,TMS等脑刺激方法与扩散张量成像相结合,可以深入了解这种疾病的病理生理学。这些见解有助于开发更有效的治疗方法。