Institute of Neurology, Magna Græcia University, Catanzaro, Italy.
Neurol Sci. 2013 Nov;34(11):2047-50. doi: 10.1007/s10072-013-1356-2. Epub 2013 Mar 15.
Although in literature almost 150 patients with Lance-Adams Syndrome (LAS) have been reported, neuroradiological evaluations were often performed in late stages and there is no serial study evaluating LAS from early stages. We herein report a serial neuroimaging study demonstrating early and transient involvement of cerebellum and thalami in a LAS patient. We may hypothesize that a transient cerebral hypoxia provoked a permanent synaptic rearrangements of the neuronal networks involved in the pathogenesis of post-hypoxic myoclonus in our patient.
尽管文献中已经报道了近 150 例 Lance-Adams 综合征（LAS）患者，但神经影像学评估往往在晚期进行，并且没有对 LAS 进行早期阶段的连续研究。我们在此报告了一项连续的神经影像学研究，该研究显示了 LAS 患者小脑和丘脑的早期和短暂受累。我们可以假设，短暂的脑缺氧引起了涉及缺氧后肌阵挛发病机制的神经元网络的永久性突触重排。
