在胺存在的情况下使用氧鎓盐对醇进行化学选择性氧化。
Chemoselective Oxidation of Alcohols in the Presence of Amines Using an Oxoammonium Salt.
作者信息
Lewis Stephonda G, Dadum Abra G, McLean David, Buenavista Jhennalin, Myers Jaileen, Lambert Kyle M, Fair Justin D
机构信息
Department of Chemistry and Biochemistry, Old Dominion University, Norfolk, Virginia, 23529, United States.
Maida Department of Chemistry, Biochemistry, Physics and Engineering, Indiana University of Pennsylvania, Indiana, Pennsylvania 15705, United States.
出版信息
Tetrahedron. 2023 Jan 26;131. doi: 10.1016/j.tet.2022.133226. Epub 2022 Dec 17.
Abstract
The oxidation of alcohols in the presence of reactive amines employing the commercially available oxoammonium cation, "Bobbitt's salt" is described. The oxidation is accomplished under acidic conditions and subsequent treatment with a suitable base affords a convenient one-pot method to access imines in good to excellent isolated yields (74-99%).
摘要
描述了在有反应性胺存在的情况下，使用市售的氧鎓阳离子“博比特盐”对醇进行氧化的过程。该氧化反应在酸性条件下完成，随后用合适的碱处理，提供了一种方便的一锅法，以良好至优异的分离产率（74 - 99%）获得亚胺。
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