老年抑郁症和痴呆症患者的血小板单胺氧化酶活性

Platelet MAO activity in geriatric patients with depression and dementia.

作者信息

Alexopoulos G S, Young R C, Lieberman K W, Shamoian C A

机构信息

Department of Psychiatry, New York Hospital-Cornell Medical Center, Cornell University Medical College, White Plains 10605.

出版信息

Am J Psychiatry. 1987 Nov;144(11):1480-3. doi: 10.1176/ajp.144.11.1480.

DOI:10.1176/ajp.144.11.1480

PMID:3674232

Abstract

The authors studied platelet MAO activity in psychiatrically hospitalized geriatric patients with depression and dementia. Platelet MAO activity was higher in demented patients with and without depression and in depressed patients with reversible dementia than in nondemented depressed patients. The data suggest that abnormally high platelet MAO activity may reflect a predisposition to the development of a dementia syndrome.

摘要

作者研究了患有抑郁症和痴呆症的老年精神科住院患者的血小板单胺氧化酶（MAO）活性。患有或未患抑郁症的痴呆患者以及患有可逆性痴呆的抑郁症患者的血小板MAO活性高于未患痴呆症的抑郁症患者。数据表明，异常高的血小板MAO活性可能反映了痴呆综合征发生的易感性。