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泰国诗琳通公主殿下医学中心(MSMC)经鼻食管镜检查在喉咽反流患者中的疗效

The Efficacy of Transnasal Esophagoscopy in Laryngopharyngeal Reflux Patients at HRH Princess Maha Chakri Sirindhorn Medical Center (MSMC), Thailand.

作者信息

Shoowit Parkkapus, Wanichakorntrakul Pisit, Wongwattana Panuwat

机构信息

Department of Otolaryngology, Faculty of Medicine, Srinakharinwirot University, Sukhumvit 23, Watana, Bangkok, 10110 Thailand.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):4906-4910. doi: 10.1007/s12070-021-02425-y. Epub 2021 Feb 13.

Abstract

To evaluate the positive pathological findings, patient satisfaction, pain, and complications of transnasal esophagoscopy (TNE) in laryngopharyngeal reflux (LPR) patients at HRH Princess Maha Chakri Sirindhorn Medical Center (MSMC), Thailand. A descriptive cross-sectional study. Forty adult LPR patients who had failed 3-months proton-pump inhibitor therapy were recruited to undergo TNE at Otolaryngology department, MSMC from January 1, 2019 to December 31, 2019. Data including demographics, Reflux Finding Score, Reflux Symptom Index, Eating Assessment Tool (EAT-10) scores, and endoscopic findings were recorded and compared between patients who had positive pathological findings and those who had negative findings. Sixteen patients (40%) had positive findings, which led to the changes in management of their conditions. Most positive findings included multiple esophageal and gastric ulcers (4/16), gastric ulcer (3/16), esophagitis (2/16), and esophageal candidiasis (2/16). There was no statistically significant difference in the baseline data between patients in the TNE positive and the TNE negative groups. The average patient satisfaction on VAS was 8.60 ± 1.43. Most patients were in the mild pain score group (18/40). Complications were not encountered. TNE is an efficient tool for evaluating LPR in Thai patients. The procedure was proven to be safe, well tolerated, and highly satisfied.

摘要

为评估泰国诗琳通公主殿下医疗中心(MSMC)喉咽反流(LPR)患者经鼻食管镜检查(TNE)的阳性病理结果、患者满意度、疼痛及并发症情况。进行一项描述性横断面研究。招募40例接受3个月质子泵抑制剂治疗无效的成年LPR患者,于2019年1月1日至2019年12月31日在MSMC耳鼻喉科接受TNE检查。记录包括人口统计学数据、反流发现评分、反流症状指数、进食评估工具(EAT - 10)评分及内镜检查结果等数据,并对病理结果阳性和阴性的患者进行比较。16例患者(40%)有阳性结果,这导致了其病情管理的改变。多数阳性结果包括多发食管和胃溃疡(4/16)、胃溃疡(3/16)、食管炎(2/16)和食管念珠菌病(2/16)。TNE阳性组和TNE阴性组患者的基线数据无统计学显著差异。患者视觉模拟评分法(VAS)的平均满意度为8.60±1.43。多数患者处于轻度疼痛评分组(18/40)。未出现并发症。TNE是评估泰国患者LPR的有效工具。该检查被证明是安全的,耐受性良好,且患者满意度高。

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本文引用的文献

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Evaluation and management of laryngopharyngeal reflux.喉咽反流的评估与管理
JAMA. 2005 Sep 28;294(12):1534-40. doi: 10.1001/jama.294.12.1534.
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Perspectives in laryngopharyngeal reflux: an international survey.喉咽反流的观点:一项国际调查。
Laryngoscope. 2002 Aug;112(8 Pt 1):1399-406. doi: 10.1097/00005537-200208000-00014.

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