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Pharmacodynamic appraisal of wound-healing herbs of .

作者信息

Kumar Vishal, Nesari Tanuja Manoj, Ghildiyal Shivani, Sherkhane Rahul

机构信息

Department of Dravyaguna, All India Institute of Ayurveda, New Delhi, India.

出版信息

Ayu. 2021 Jan-Mar;42(1):1-18. doi: 10.4103/ayu.AYU_34_20. Epub 2022 Dec 7.

Abstract

BACKGROUND

In , various medicinal plants as single and compound formulations having (wound cleansing) and (wound healing) potential are enumerated. There are no published data available on these wound-healing medicinal plants of . The effectivee management of wound is necessary in the immunocompromised and chronic wounds patients as they take more time to heal.

AIM

To review and systematically analyze wound-healing medicinal plants and their modus-operandi on the basis of pharmacodynamics attributes, i.e., (taste) (potency), and (biotransformation) in the various stages of healing.

MATERIALS AND METHODS

Review of was done to gather wound-healing medicinal plants; pharmacodynamics attributes were gatherd from various to understand their role in wound healing. The contemporary information about wound-healing mechanism was gathered from PubMed to interpitate the rational use of plants in the various stages of wound healing.

RESULTS

The study suggests that 43 medicinal plants have activity, 48 have and 62 have both and potential. Medicinal plants with - category are having predominance of (pungent), (bitter) and (astriengent) . Plants under are having (sweet taste) (sweet biotransform) and (cold potency).

CONCLUSION

Plants having , and may be useful in the inflammatory stage, plants having and may be useful in the prolifiratory stage and plants having , and may be useful in the remodeling stage. The present review will help to give the directions to the researchers for the development of effective wound-healing medicines for wounds.

摘要

背景

在[具体地区或研究范围未明确],列举了各种作为单一和复方制剂具有清创(伤口清洁)和促愈(伤口愈合)潜力的药用植物。关于[该地区或范围]这些伤口愈合药用植物尚无已发表的数据。在免疫功能低下和慢性伤口患者中,伤口的有效管理是必要的,因为他们愈合所需时间更长。

目的

根据药效学属性,即味(味道)、效能和生物转化,在愈合的各个阶段对伤口愈合药用植物及其作用方式进行综述和系统分析。

材料与方法

对[相关文献或资源未明确]进行综述以收集伤口愈合药用植物;从各种[来源未明确]收集药效学属性以了解它们在伤口愈合中的作用。从PubMed收集有关伤口愈合机制的当代信息,以解释植物在伤口愈合各个阶段的合理使用。

结果

研究表明,43种药用植物具有清创活性,48种具有促愈活性,62种同时具有清创和促愈潜力。具有-类别的药用植物以辛(辛辣)、苦(苦味)和涩(收敛)味为主。类别的植物具有甘(甜味)、甘(甜生物转化)和寒(寒效能)。

结论

具有辛、苦、涩味的植物可能在炎症阶段有用,具有甘、寒属性的植物可能在增殖阶段有用,具有其他特定味道和效能组合的植物可能在重塑阶段有用。本综述将有助于为研究人员开发有效的伤口愈合药物提供方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e261/9893898/e62324c12171/AYU-42-1-g001.jpg

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