Yadav Uttamram, Bhatted Santosh Kumar
Department of Panchakarma, All India Institute of Ayurveda, New Delhi, India.
Ayu. 2021 Jan-Mar;42(1):30-34. doi: 10.4103/ayu.ayu_417_20. Epub 2022 Dec 7.
Prediabetes is an alarming condition to control and prevent from developing diabetes mellitus which occurs due to the change in lifestyle and food habits. Timely untreated prediabetes turn into type-2 diabetes mellitus within a year and systemic complications such as retinopathy, nephropathy, and neuropathy could occur and in later stage multi system damage could take place.
The ai of this study is to evaluate the efficacy of (therapeutic emesis) with and followed by oral administration of (herbal decoction) in the management of prediabetes.
After approval of IEC and registration under clinical trial registry of India, 20 patients suffering from prediabetes were registered in the trial. Diagnosis criteria were hemoglobin A1c (HBA1c), fasting blood sugar (FBS) and postprandial blood sugar (PPBS), and assessment criteria includes HBA1c, FBS, PPBS, along with improvement in (strength of digestion and metabolism), (physical strength) and (mental strength), relief sign and symptom of prediabetes (), and improvement in quality of life (SF-36 Score). Classical followed by oral administration of was done. Total duration of treatment was 45 days and last follow-up was done on the 120 day. Student's - test was used for the analysis of parametric data.
After the treatment were observed that there is improvement in subjective as well as in objective parameters. Statistically highly significant result was observed in HBA1c (BT [day 0] Mean score 6.25 and AT [day 120] 5.63 [ < 0.001]), FBS (BT [day 0] mean score 120.05 and AT [day 120] 93.31 [ < 0.001]) and PPBS (BT [day 0] mean score 165.26 and AT [day 120] 112.84 [ < 0.001]), sign and symptoms of , and quality of life (SF-36 Score).
The present clinical study concludes that therapeutic emesis (bio purification) followed by as internal medicine shows significant result in treating prediabetes () safely and effectively also control and prevent developing diabetes mellitus. None of the patient converted to diabetes mellitus on the day 120.
糖尿病前期是一种需要加以控制并预防发展为糖尿病的警示状态，其因生活方式和饮食习惯的改变而发生。未经及时治疗的糖尿病前期会在一年内发展为2型糖尿病，还可能出现视网膜病变、肾病和神经病变等全身性并发症，后期可能发生多系统损害。
本研究的目的是评估（治疗性呕吐）联合随后口服（草药煎剂）在糖尿病前期管理中的疗效。
经印度伦理委员会批准并在印度临床试验注册中心注册后，20例糖尿病前期患者被纳入该试验。诊断标准为糖化血红蛋白（HBA1c）、空腹血糖（FBS）和餐后血糖（PPBS），评估标准包括HBA1c、FBS、PPBS，以及（消化和代谢能力）、（体力）和（精神力量）的改善、糖尿病前期的体征和症状（）的缓解，以及生活质量的改善（SF - 36评分）。采用经典的（治疗性呕吐）联合随后口服（草药煎剂）的方法。治疗总时长为45天，最后一次随访在第120天进行。采用学生t检验分析参数数据。
治疗后观察到主观和客观参数均有改善。在糖化血红蛋白（治疗前[第0天]平均得分6.25，治疗后[第120天]5.63[<0.001]）、空腹血糖（治疗前[第0天]平均得分120.05，治疗后[第120天]93.31[<0.001]）和餐后血糖（治疗前[第0天]平均得分165.26，治疗后[第120天]112.84[<0.001]）、（相关体征和症状）以及生活质量（SF - 36评分）方面观察到具有统计学高度显著性的结果。
本临床研究得出结论，先进行治疗性呕吐（生物净化）然后以内科方式使用（草药煎剂）在安全有效地治疗糖尿病前期（）以及控制和预防糖尿病发展方面显示出显著效果。在第120天时没有患者发展为糖尿病。
