Prajapati Rakesh P, Kalariya Manisha, Parmar Sachin K, Sheth Navin R
Saurashtra University, Rajkot, Gujarat, India.
J Ayurveda Integr Med. 2010 Oct;1(4):266-72. doi: 10.4103/0975-9476.74431.
Lagenaria siceraria (Molina) standley (LS) (Family: Cucurbitaceae) is an annual herbaceous climbing plant with a long history of traditional medicinal uses in many countries, especially in tropical and subtropical regions. Since ancient times the climber has been known for its curative properties, and has been utilized for treatment of various ailments, including jaundice, diabetes, ulcer, piles, colitis, insanity, hypertension, congestive cardiac failure (CCF), and skin diseases. Its fruit pulp is used both as an emetic and purgative, and for its cooling, diuretic, antibilious, and pectoral properties. Boiled in oil this pulp is used to treat rheumatism and insomnia. A wide range of chemical compounds including sterols, terpenoids, flavonoids, and saponins have been isolated from the species. Its extracts have been found to possess various pharmacological activities. Below, we give a comprehensive review of its ethnomedical uses, chemical constituents, and pharmacological profile as a medicinal plant. Particular attention is given to its analgesic, anti-inflammatory, antihyperlipidemic, diuretic, hepatoprotective, anthelmintic, and antibacterial effects so that its potential uses in pharmaceutics can be better evaluated.
葫芦（Lagenaria siceraria (Molina) standley (LS)，葫芦科）是一种一年生草本攀缘植物，在许多国家，特别是热带和亚热带地区有着悠久的传统药用历史。自古以来，这种攀缘植物就因其治疗功效而闻名，并被用于治疗各种疾病，包括黄疸、糖尿病、溃疡、痔疮、结肠炎、精神病、高血压、充血性心力衰竭（CCF）和皮肤病。其果肉既用作催吐剂和泻药，也因其具有清凉、利尿、利胆和祛痰的特性而被使用。这种果肉在油中煮沸后用于治疗风湿病和失眠。已从该物种中分离出多种化合物，包括甾醇、萜类化合物、黄酮类化合物和皂苷。已发现其提取物具有多种药理活性。下面，我们对其作为药用植物的民族医学用途、化学成分和药理特性进行全面综述。特别关注其镇痛、抗炎、抗高血脂、利尿、保肝、驱虫和抗菌作用，以便能更好地评估其在制药方面的潜在用途。
