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一例因肺动静脉瘘导致的反常脑栓塞,酷似椎动脉夹层伴延髓背外侧综合征

A Case of Paradoxical Cerebral Embolism Due to Pulmonary Arteriovenous Fistula Mimicking Vertebral Artery Dissection With Wallenberg Syndrome.

作者信息

Isogai Masaru, Suzuki Tomoaki, Kato Shyunichi, Taniguchi Yoshinori, Hasegawa Hitoshi, Oishi Makoto, Fujii Yukihiko

机构信息

Department of Neurosurgery, Nagaoka Chuo General Hospital, Nagaoka, JPN.

Department of Neurosurgery, Niigata University, Brain Research Institute, Niigata, JPN.

出版信息

Cureus. 2023 Feb 2;15(2):e34564. doi: 10.7759/cureus.34564. eCollection 2023 Feb.

Abstract

Pulmonary arteriovenous fistula (PAVF) leads to paradoxical cerebral embolism, which can be fatal if left untreated. We report a rare case of brainstem infarction with acute severe headache and Wallenberg syndrome caused by a PAVF mimicking vertebral artery (VA) dissection. A 40-year-old man presented with a sudden occipital headache accompanied by right hemisensory disturbance. Magnetic resonance imaging revealed left lateral medullary infarction and poor depiction of the left VA. However, it was clearly recanalized on day six, and there were no findings of VA dissection. Whole-body contrast-enhanced computed tomography (CT) revealed a PAVF in the right lung and a thrombus in the feeding artery. The patient was diagnosed with hereditary hemorrhagic telangiectasia due to recurrent epistaxis and peripheral vasodilation of the tongue. An anticoagulant was administered for preventing further ischemic stroke, and a follow-up CT confirmed the disappearance of the thrombus in three months. Thoracoscopic partial lung resection was performed five months after the onset, and no recurrence of ischemic stroke was observed.

摘要

肺动静脉瘘(PAVF)可导致反常性脑栓塞,若不治疗可能致命。我们报告一例罕见的由PAVF模拟椎动脉(VA)夹层引起的伴有急性重度头痛和延髓背外侧综合征的脑干梗死病例。一名40岁男性突发枕部头痛并伴有右侧半身感觉障碍。磁共振成像显示左侧延髓外侧梗死且左侧VA显示不清。然而,在第6天其明显再通,且未发现VA夹层的表现。全身对比增强计算机断层扫描(CT)显示右肺有一个PAVF且供血动脉内有血栓形成。该患者因反复鼻出血和舌部外周血管扩张被诊断为遗传性出血性毛细血管扩张症。给予抗凝剂以预防进一步的缺血性卒中,随访CT证实3个月后血栓消失。发病5个月后进行了胸腔镜下部分肺切除术,未观察到缺血性卒中复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f6d/9896129/6cf964f27979/cureus-0015-00000034564-i01.jpg

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