Nassarmadji Kladoum, Vanjak Anthony, Bourdin Venceslas, Champion Karine, Burlacu Ruxandra, Mouly Stéphane, Sène Damien, Comarmond Cloé
Department of Internal Medicine and Clinical Immunology, Lariboisière Hospital, Université Paris Cité, Paris, France.
Front Med (Lausanne). 2023 Jan 19;10:1103752. doi: 10.3389/fmed.2023.1103752. eCollection 2023.
Diagnosis, prognostic assessment, and monitoring disease activity in patients with large vessel vasculitis (LVV) can be challenging. Early recognition of LVV and treatment adaptation is essential because vascular complications (aneurysm, dilatations, ischemic complications) or treatment related side effects can occur frequently in these patients. 18-fluorodeoxyglucose positron emission tomography/computed tomography (2-[18F]FDG-PET/CT) is increasingly used to diagnose, follow, and evaluate treatment response in LVV. In this review, we aimed to summarize the current evidence on the value of 2-[18F]FDG-PET/CT for diagnosis, follow, and treatment monitoring in LVV.
诊断、预后评估以及监测大血管血管炎(LVV)患者的疾病活动情况可能具有挑战性。早期识别LVV并调整治疗至关重要,因为这些患者经常会出现血管并发症(动脉瘤、扩张、缺血性并发症)或与治疗相关的副作用。18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(2-[18F]FDG-PET/CT)越来越多地用于诊断、随访和评估LVV的治疗反应。在本综述中,我们旨在总结当前关于2-[18F]FDG-PET/CT在LVV诊断、随访和治疗监测方面价值的证据。