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用于高性能可穿戴电源及葡萄糖实时监测的二维双金属有机框架纳米片

2D bimetallic organic framework nanosheets for high-performance wearable power source and real-time monitoring of glucose.

作者信息

Zha Xiaoting, Yang Wenyao, Shi Liuwei, Zeng Qi, Xu Jianhua, Yang Yajie

机构信息

School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054, China.

Chongqing Engineering Research Center of New Energy Storage Devices and Applications, Chongqing University of Arts and Sciences, Chongqing, 402160, China.

出版信息

Dalton Trans. 2023 Feb 28;52(9):2631-2640. doi: 10.1039/d2dt03311a.

Abstract

Diabetics often prick their fingertips to measure the glucose levels in their blood. However, this traditional method not only causes prolonged pain but also increases the risk of infection. Hence, in this study, a non-invasive flexible glucose biosensor with high sensitivity was fabricated. Specifically, NiCo metal-organic frameworks (NiCo-MOFs) served as the electrode material of a micro-supercapacitor and sensing material of a glucose sensor. The electrochemical tests verified that the prominent sensitivity of the NiCo bimetal product is 1422.2 μA mM cm. The micro-supercapacitor based on the as-fabricated NiCo-MOFs showed a high energy density of 11.5 mW h cm at the power density 0.26 mW cm. In addition, the as-designed glucose device exhibited an excellent sensitivity of 0.31 μA μM. Furthermore, a flexible energy storage and glucose detection system was successfully prepared by further integrating the micro-supercapacitor and glucose sensor. The smart detector could accurately and conveniently measure the glucose concentration in sweat in real-time. Therefore, the wearable real-time sensing device displays feasible application for non-invasive glucose monitoring and health management.

摘要

糖尿病患者经常刺破指尖来测量血糖水平。然而,这种传统方法不仅会导致长时间疼痛,还会增加感染风险。因此,在本研究中,制备了一种具有高灵敏度的非侵入式柔性葡萄糖生物传感器。具体而言,镍钴金属有机框架(NiCo-MOFs)用作微型超级电容器的电极材料和葡萄糖传感器的传感材料。电化学测试证实,镍钴双金属产物的突出灵敏度为1422.2 μA mM cm 。基于所制备的NiCo-MOFs的微型超级电容器在功率密度为0.26 mW cm 时显示出11.5 mW h cm 的高能量密度。此外,所设计的葡萄糖装置表现出0.31 μA μM的优异灵敏度。此外,通过进一步集成微型超级电容器和葡萄糖传感器,成功制备了一种柔性储能和葡萄糖检测系统。该智能探测器可以实时准确、方便地测量汗液中的葡萄糖浓度。因此,这种可穿戴实时传感装置在非侵入式葡萄糖监测和健康管理方面显示出可行的应用前景。

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