快速无痕：Prx1+成纤维细胞加速愈合。
Fast and scarless: Prx1+ fibroblasts turbocharge healing.
机构信息
Department of Microbiology, NYU Langone Health , New York, NY, USA.
Department of Pathology, Department of Medicine, Ronald O. Perelman Department of Dermatology, and Perlmutter Cancer Center, NYU Langone Health , New York, NY, USA.
出版信息
J Exp Med. 2023 Mar 6;220(3). doi: 10.1084/jem.20222139. Epub 2023 Feb 6.
Abstract
Our oral cavity has evolved a capacity for rapid healing without scarring. In this issue of JEM, Ko et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20221350) identify a Prx1+ fibroblast progenitor that drives oral regeneration by summoning pro-healing TGFβ1+ macrophages.
摘要
我们的口腔具有快速愈合而无瘢痕的能力。在本期《实验医学杂志》中，Ko 等人（2022. J. Exp. Med.https://doi.org/10.1084/jem.20221350）发现了一种 Prx1+成纤维细胞祖细胞，它通过召唤促愈合的 TGFβ1+巨噬细胞来驱动口腔再生。
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