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评估在门诊环境中对老年患者进行多方面药物审查的效果:一项前后对照研究。

Evaluation of a multifaceted medication review in older patients in the outpatient setting: a before-and-after study.

机构信息

Department of Geriatric Medicine, Laurentius Hospital, Roermond, The Netherlands.

Department of Hospital Pharmacy, Erasmus Medical Centre, Rotterdam, The Netherlands.

出版信息

Int J Clin Pharm. 2023 Apr;45(2):483-490. doi: 10.1007/s11096-022-01531-3. Epub 2023 Feb 6.

DOI:10.1007/s11096-022-01531-3
PMID:36745311
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10147805/
Abstract

BACKGROUND

The prevalence of medication-related emergency department visits and acute hospital admissions in older patients is rising due to the ageing of the population and increasing prevalence of multimorbidity and associated polypharmacy.

AIM

To explore whether a combined medication review performed in the outpatient setting reduces the number of medication-related emergency department visits and hospital (re)admissions.

METHOD

All consecutive patients visiting the geriatric outpatient clinic underwent a multifaceted medication review (i.e. evaluation by at least a geriatrician, and/or pharmacist and use of clinical decision support system). Subsequently, we analysed the number of, and reason for, emergency department visits, acute hospital admissions and readmissions in the year prior to and the year following the index-date (date of first presentation and medication review).

RESULTS

A multifaceted medication review reduced the number of potentially medication-related emergency department visits (38.9% vs. 19.6%, p < 0.01), although the total number of ED visits or acute hospital admissions per patient in the year before and after medication review did not differ.

CONCLUSION

A multifaceted medication review performed in the outpatient clinic reduced the number of potentially medication-related emergency department visits and could therefore reduce negative health outcomes and healthcare costs.

摘要

背景

由于人口老龄化以及多种疾病和相关多药治疗的患病率增加,老年患者因药物相关而到急诊就诊和急性住院的情况越来越多。

目的

探讨在门诊环境中进行联合药物审查是否可以减少与药物相关的急诊就诊和医院(再)入院的次数。

方法

所有连续到老年门诊就诊的患者都接受了多方面的药物审查(即至少由老年病医生和/或药剂师进行评估,以及使用临床决策支持系统)。随后,我们分析了索引日期(首次就诊和药物审查日期)之前和之后一年中,急诊就诊、急性住院和再入院的次数和原因。

结果

多方面的药物审查减少了潜在与药物相关的急诊就诊次数(38.9% 比 19.6%,p < 0.01),尽管药物审查前后每位患者的急诊就诊次数或急性住院入院次数没有差异。

结论

在门诊环境中进行的多方面药物审查减少了潜在与药物相关的急诊就诊次数,因此可以降低不良健康结果和医疗保健成本。

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Drug-related emergency department visits: prevalence and risk factors.与药物相关的急诊科就诊:患病率及危险因素。
Intern Emerg Med. 2022 Aug;17(5):1453-1462. doi: 10.1007/s11739-022-02935-9. Epub 2022 Feb 7.
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Medication review interventions to reduce hospital readmissions in older people.药物审查干预措施以减少老年人的住院再入院率。
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Professional, structural and organisational interventions in primary care for reducing medication errors.在初级保健中采取专业、结构和组织干预措施以减少用药错误。
Cochrane Database Syst Rev. 2017 Oct 4;10(10):CD003942. doi: 10.1002/14651858.CD003942.pub3.
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Effectiveness of medication review: a systematic review and meta-analysis of randomized controlled trials.药物评估的有效性:随机对照试验的系统评价与荟萃分析
BMC Fam Pract. 2017 Jan 17;18(1):5. doi: 10.1186/s12875-016-0577-x.
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Do pharmacist-led medication reviews in hospitals help reduce hospital readmissions? A systematic review and meta-analysis.医院中由药剂师主导的用药评估是否有助于减少再次入院?一项系统评价与荟萃分析。
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Effectiveness of pharmacist-led medication reconciliation programmes on clinical outcomes at hospital transitions: a systematic review and meta-analysis.药剂师主导的药物重整计划在医院转衔期间对临床结局的有效性:系统评价和荟萃分析。
BMJ Open. 2016 Feb 23;6(2):e010003. doi: 10.1136/bmjopen-2015-010003.
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