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扳机指疗效的国家基准及相关失败风险因素。

National Benchmarks for the Efficacy of Trigger Finger and the Risk Factors Associated With Failure.

机构信息

From the Department of Orthopaedic Surgery and Rehabilitation Medicine, University of Chicago Medicine, Chicago, IL (Ms. Lewis); Pritzker School of Medicine at The University of Chicago, Chicago, IL (Mr. Seidel); and Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago, Chicago, IL (Dr. Shi, Dr. Wolf, and Dr. Strelzow).

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2023 Feb 3;7(2). doi: 10.5435/JAAOSGlobal-D-22-00198. eCollection 2023 Feb 1.

Abstract

BACKGROUND

The purpose of this study was to compare the efficacy of single and multiple corticosteroid injections used for symptomatic trigger finger. The rates of subsequent injections and the rate of tendon sheath release are reported along with the identification of risk factors correlated with failure of injection.

METHODS

A retrospective review of a national healthcare database was conducted identifying patients with a diagnosis of trigger finger or thumb. Inclusion required a tendon sheath injection on the same day or within six weeks of diagnosis. Patient cohorts were further stratified based on treatment success and those requiring additional injections within 6 months or surgery within 1 year of initial diagnosis.

RESULTS

Thirty-one thousand seven hundred fifty-one patients met inclusion criteria and underwent an initial injection within the study period. The efficacy of initial, second, and third injection was 66.3%, 79.4%, and 79.6%, respectively. Of the patients who failed an injection, 9.4% had tendon sheath release after a primary injection, 23.1% had surgery after a second injection, and 30.4% had surgery after a third injection. Only obesity (OR 1.2; P < 0.0001) and concomitant diagnosis of carpal tunnel syndrome (OR 1.4; P < 0.0001) were found to be significant for injection failure on multivariate logistic regression analysis.

DISCUSSION

Overall corticosteroid injections were effective in greater than 65% of patients. This information may help guide treatment practice because there seems to be continued additional benefit to repeat corticosteroid injections after injection failure.

摘要

背景

本研究旨在比较单次和多次皮质类固醇注射治疗症状性扳机指的疗效。报告了后续注射率和腱鞘松解率,并确定了与注射失败相关的危险因素。

方法

对国家医疗保健数据库进行回顾性研究,确定诊断为扳机指或拇指的患者。纳入标准为在诊断当天或 6 周内进行腱鞘注射。根据治疗成功情况进一步分层患者队列,将在 6 个月内需要额外注射或在初始诊断后 1 年内需要手术的患者分为不同亚组。

结果

31751 名患者符合纳入标准,并在研究期间接受了初次注射。初次、第二次和第三次注射的疗效分别为 66.3%、79.4%和 79.6%。在注射失败的患者中,9.4%在初次注射后行腱鞘松解术,23.1%在第二次注射后行手术,30.4%在第三次注射后行手术。只有肥胖(OR 1.2;P<0.0001)和同时诊断为腕管综合征(OR 1.4;P<0.0001)在多变量逻辑回归分析中被发现与注射失败显著相关。

讨论

总体而言,皮质类固醇注射在超过 65%的患者中有效。这些信息可能有助于指导治疗实践,因为在注射失败后重复皮质类固醇注射似乎会继续带来额外的益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddc3/9902002/f7cf2159d81d/jagrr-7-e22.00198-g001.jpg

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