Department of Ultrasound, Zhongshan Hospital of Fudan University (Qingpu Branch), Shanghai, China.
Department of Ultrasound, Zhongshan Hospital of Fudan University, Shanghai, China.
BMC Med Imaging. 2023 Feb 6;23(1):26. doi: 10.1186/s12880-023-00982-y.
To verify whether radiomics techniques based on dual-modality ultrasound consisting of B-mode and superb microvascular imaging (SMI) can improve the accuracy of the differentiation between gallbladder neoplastic polyps and cholesterol polyps.
A total of 100 patients with 100 pathologically proven gallbladder polypoid lesions were enrolled in this retrospective study. Radiomics features on B-mode ultrasound and SMI of each lesion were extracted. Support vector machine was used to classify adenomas and cholesterol polyps of gallbladder for B-mode, SMI and dual-modality ultrasound, respectively, and the classification results were compared among the three groups.
Six, eight and nine features were extracted for each lesion at B-mode ultrasound, SMI and dual-modality ultrasound, respectively. In dual-modality ultrasound model, the area under the receiver operating characteristic curve (AUC), classification accuracy, sensitivity, specificity, and Youden's index were 0.850 ± 0.090, 0.828 ± 0.097, 0.892 ± 0.144, 0.803 ± 0.149 and 0.695 ± 0.157, respectively. The AUC and Youden's index of the dual-modality model were higher than those of the B-mode model (p < 0.05). The AUC, accuracy, specificity and Youden's index of the dual-modality model were higher than those of the SMI model (p < 0.05).
Radiomics analysis of the dual-modality ultrasound composed of B-mode and SMI can improve the accuracy of classification between gallbladder neoplastic polyps and cholesterol polyps.
验证基于包含 B 型和超微血流成像（SMI）的双模态超声的放射组学技术是否可以提高胆囊肿瘤性息肉和胆固醇息肉之间鉴别诊断的准确性。
本回顾性研究共纳入 100 例经病理证实的胆囊息肉样病变患者。对每个病变的 B 型超声和 SMI 的放射组学特征进行提取。使用支持向量机分别对 B 型超声、SMI 和双模态超声对胆囊腺瘤和胆固醇息肉进行分类，并比较三组的分类结果。
B 型超声、SMI 和双模态超声分别对每个病变提取了 6、8 和 9 个特征。在双模态超声模型中，受试者工作特征曲线下面积（AUC）、分类准确率、敏感度、特异度和约登指数分别为 0.850±0.090、0.828±0.097、0.892±0.144、0.803±0.149 和 0.695±0.157。双模态模型的 AUC 和约登指数高于 B 型模型（p<0.05）。双模态模型的 AUC、准确率、特异度和约登指数均高于 SMI 模型（p<0.05）。
由 B 型和 SMI 组成的双模态超声的放射组学分析可以提高胆囊肿瘤性息肉和胆固醇息肉之间分类的准确性。
