Department of General Surgery, University of Health Sciences, Gülhane Training and Research Hospital, Ankara-Türkiye.
Ulus Travma Acil Cerrahi Derg. 2023 Feb;29(2):183-192. doi: 10.14744/tjtes.2022.20093.
Emergency anterior abdominal wall hernia surgery plays a pivotal role in emergency general surgery practice. In this study, the predictive value of laboratory and imaging findings as well as demographic information and comorbidities of the patients for the recognition of strangulation and intestinal resection was investigated.
Patients over the age of 18 who were operated consecutively with an indication for emergency anterior abdominal wall hernia surgery between January 2017 and December 2019 in a single tertiary hospital were included in this retrospective cohort study. The patient population was divided into two groups according to the pre-operative findings during the emergency anterior abdominal wall hernia surgery. Group 1 consisted of cases with incarceration but without strangulation, whereas Group 2 consisted of cases with strangulation in addition to incarceration. Moreover, in evaluation for the requirement for intestinal resection, patient Group 2 was divided further into two groups, namely, as Group (1 or 2) a and Group (1 or 2) b, defining the need for intestinal resection.
A total of 106 patients who had emergency anterior abdominal wall repair surgery due to incarcerated hernias were included in the study. The evaluation of the indices related to systemic inflammation revealed that lactate dehydrogenase to white blood cell ratio was significantly lower but neutrophil to platelet and neutrophil to albumin ratios were significantly higher in patients with strangulation, showing the significance of those systemic inflammation indices in detecting strangulation (p=0.027, p=0.035 and p=0.030, respectively). Moreover, the analysis of the patients in whom intestinal resection was required (Group 2a vs. 2b) exposed that neutrophil to albumin ratio was significantly higher in the patients with intestinal resection (p=0.036).
Indices of systemic inflammation such as lactate dehydrogenase to white blood cell ratio, neutrophil to platelet ratio, and particularly neutrophil to albumin ratio may be potentially beneficial to prevent complications and improve clinical outcomes in emergency hernia surgery.
急诊腹壁疝修补术在普通外科急症实践中起着关键作用。本研究旨在探讨实验室和影像学检查结果以及患者的人口统计学信息和合并症对绞窄和肠切除识别的预测价值。
本回顾性队列研究纳入了 2017 年 1 月至 2019 年 12 月期间在一家三级医院因急诊腹壁疝手术指征连续接受手术的 18 岁以上患者。根据急诊腹壁疝手术前的检查结果,将患者人群分为两组。第 1 组为嵌顿但无绞窄的病例,第 2 组为嵌顿伴绞窄的病例。此外,在评估肠切除的必要性时,第 2 组患者进一步分为第(1 或 2)a 组和第(1 或 2)b 组,以确定肠切除的必要性。
共有 106 例因嵌顿疝而行急诊腹壁修复手术的患者纳入本研究。评估与全身炎症相关的指标显示,乳酸脱氢酶与白细胞比值在绞窄患者中显著降低,但中性粒细胞与血小板比值和中性粒细胞与白蛋白比值显著升高,这些全身炎症指标在检测绞窄方面具有重要意义(p=0.027、p=0.035 和 p=0.030)。此外,对需要肠切除的患者(第 2 组 a 与 2 组 b)进行分析,发现中性粒细胞与白蛋白比值在需要肠切除的患者中显著升高(p=0.036)。
乳酸脱氢酶与白细胞比值、中性粒细胞与血小板比值,特别是中性粒细胞与白蛋白比值等全身炎症指标可能有助于预防并发症并改善急诊疝手术的临床结局。