• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

高度近视眼中的多发性消失性白点综合征,眼底自发荧光在诊断中具有重要作用:一例报告。

Multiple evanescent white dot syndrome in highly myopic eye in which fundus autofluorescence was diagnostically useful: A case report.

机构信息

Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu, Japan.

出版信息

Medicine (Baltimore). 2023 Feb 3;102(5):e32713. doi: 10.1097/MD.0000000000032713.

DOI:10.1097/MD.0000000000032713
PMID:36749227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9901977/
Abstract

RATIONALE

Multiple evanescent white dot syndrome (MEWDS) is characterized by multiple white dots in the posterior pole of the eye, but its diagnosis can be difficult in cases when the white dots are not visible. We report an atypical case of MEWDS that developed in pathologic myopia.

PATIENT CONCERN

A 42-year-old woman presented with floater and reduced and distorted vision in the right eye that she noted 3 days earlier.

DIAGNOSIS

The right eye was highly myopic at -17.0 diopters, and her decimal best-corrected visual acuity was reduced to 0.2 (20/100). Fundus examinations revealed no abnormalities other than myopic fundus changes and previous laser photocoagulation spots. However, fundus autofluorescence (FAF) showed multiple hyperfluorescent dots, and optical coherence tomography showed a high reflective lesion on the retinal pigmental epithelium at the fovea. Adjustments of the brightness and contrast of the conventional fundus images revealed white dots in the same location as the hyperfluorescent spots seen in the FAF images. We diagnosed her with MEWDS.

INTERVENTIONS

We treated her with systemic administration of 20 mg prednisolone and the dose of prednisolone was reduced by 5 mg every 4 weeks.

OUTCOMES

The optical coherence tomography and FAF findings gradually normalized, and 5 months later, her decimal visual acuity was restored to 1.0 (20/20).

LESSONS

It was suggested that white dots typical to MEWDS may not be evident in pathologic myopia, and FAF images and the brightness and contrast adjustment of fundus images were useful in the diagnosis of atypical MEWDS.

摘要

背景

多发性一过性白点综合征(MEWDS)的特征是眼后极有多发性白点,但当白点不可见时,其诊断可能较为困难。我们报告了一例病理性近视中发生的不典型 MEWDS 病例。

病例介绍

一名 42 岁女性因右眼漂浮物和视力下降(右眼视力下降 3 天前出现)就诊。

诊断

右眼高度近视达-17.0 屈光度,她的十进制最佳矫正视力降至 0.2(20/100)。眼底检查除了近视眼底改变和既往激光光凝斑外,未见其他异常。然而,眼底自发荧光(FAF)显示多个高荧光点,光学相干断层扫描(OCT)显示在黄斑区视网膜色素上皮有一个高反射病变。调整常规眼底图像的亮度和对比度后,在与 FAF 图像中高荧光点相同的位置显示出白点。我们诊断为 MEWDS。

干预措施

我们给予她全身 20mg 泼尼松龙治疗,每 4 周减少 5mg 泼尼松龙剂量。

结果

OCT 和 FAF 检查结果逐渐恢复正常,5 个月后,她的十进制视力恢复至 1.0(20/20)。

结论

提示在病理性近视中,MEWDS 的典型白点可能不明显,FAF 图像和眼底图像的亮度和对比度调整有助于诊断不典型 MEWDS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b53/9901977/7187b0b8ce6c/medi-102-e32713-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b53/9901977/5592fe76eabf/medi-102-e32713-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b53/9901977/9b10a4854b0f/medi-102-e32713-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b53/9901977/7187b0b8ce6c/medi-102-e32713-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b53/9901977/5592fe76eabf/medi-102-e32713-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b53/9901977/9b10a4854b0f/medi-102-e32713-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b53/9901977/7187b0b8ce6c/medi-102-e32713-g003.jpg

相似文献

1
Multiple evanescent white dot syndrome in highly myopic eye in which fundus autofluorescence was diagnostically useful: A case report.高度近视眼中的多发性消失性白点综合征,眼底自发荧光在诊断中具有重要作用:一例报告。
Medicine (Baltimore). 2023 Feb 3;102(5):e32713. doi: 10.1097/MD.0000000000032713.
2
Multiple Evanescent White Dot Syndrome (MEWDS) Associated with Progression of Lacquer Cracks in High Myopia.高度近视漆裂纹进展相关的多发性一过性白点综合征(MEWDS)。
Klin Monbl Augenheilkd. 2021 Oct;238(10):1098-1100. doi: 10.1055/a-1515-6065. Epub 2021 Jul 29.
3
AN ELDERLY PATIENT WITH ACUTE TRANSIENT OUTER RETINAL DISRUPTION RESEMBLING BILATERAL MULTIPLE EVANESCENT WHITE DOT SYNDROME.一位老年患者出现急性短暂性外层视网膜病变,类似于双侧多发性一过性白点综合征。
Retin Cases Brief Rep. 2020 Spring;14(2):131-136. doi: 10.1097/ICB.0000000000000665.
4
MULTIPLE EVANESCENT WHITE DOT SYNDROME WITH SUBRETINAL DEPOSITS.伴有视网膜下沉积物的多发性一过性白点综合征。
Retin Cases Brief Rep. 2019 Fall;13(4):314-319. doi: 10.1097/ICB.0000000000000602.
5
Masqueraders of multiple evanescent white dot syndrome (MEWDS).多发性一过性白点综合征(MEWDS)的伪装者。
Int Ophthalmol. 2020 Mar;40(3):627-638. doi: 10.1007/s10792-019-01223-4. Epub 2019 Dec 2.
6
Multiple Evanescent White Dot Syndrome: Findings from a Large Northern California Cohort.多发性一过性白点综合征:来自北加利福尼亚一个大型队列的研究结果。
Ophthalmol Retina. 2021 Sep;5(9):850-854. doi: 10.1016/j.oret.2020.11.016. Epub 2020 Nov 30.
7
Contralateral Recurrences of Post-vaccination Multiple Evanescent White Dot Syndrome.接种疫苗后多发性一过性白点综合征的对侧复发
Cureus. 2022 Dec 7;14(12):e32300. doi: 10.7759/cureus.32300. eCollection 2022 Dec.
8
Topographic patterns of retinal lesions in multiple evanescent white dot syndrome.多发性一过性白点综合征的视网膜病变的地形模式。
Graefes Arch Clin Exp Ophthalmol. 2023 Aug;261(8):2257-2264. doi: 10.1007/s00417-023-06032-1. Epub 2023 Mar 29.
9
AUTOFLUORESCENT TIMELINE OF SPOTS AND DOTS IN MULTIPLE EVANESCENT WHITE DOT SYNDROME.多发性一过性白点综合征中斑点和小点的自发荧光时间线
Retin Cases Brief Rep. 2022 May 1;16(3):280-284. doi: 10.1097/ICB.0000000000000974. Epub 2020 Feb 5.
10
Near-infrared fundus autofluorescence in multiple evanescent white-dot syndrome.多灶性易消散性白点综合征的近红外眼底自发荧光
Eur J Ophthalmol. 2015 Jan-Feb;25(1):43-6. doi: 10.5301/ejo.5000534. Epub 2014 Oct 30.