Institute of Chinese Medicine Literature, and Culture, Shandong University of Traditional Chinese Medicine, Jinan, China.
Peking University Medical Lu Zhong Hospital, Jinan, China.
Medicine (Baltimore). 2023 Feb 3;102(5):e32804. doi: 10.1097/MD.0000000000032804.
This study aimed to observe the clinical effects of Xiao-xian decoction combined with acupoint application therapy (AAT) for treating pediatric adenoid hypertrophy (AH).
We randomly divided 93 AH children into 3 groups: AAT alone; Xiao-xian decoction + AAT; control: Montelukast oral therapy. All participants were treated for a month. We used the traditional Chinese medicine syndrome score to evaluate the clinical efficacy and the obstructive sleep apnea-18 scale to evaluate the quality of life.
The major symptoms (nasal congestion, open mouth breathing, snoring, and tongue image) and secondary symptoms of patients treated with Xiao-xian decoction + AAT significantly improved compared to before treatment. The pairwise comparison between groups showed that snoring, tongue, secondary symptoms, and total effective rate of the combined treatment group were better than the control and AAT alone. Additionally, the open-mouth breathing, quality of life, and recurrence rate did not differ after treatment.
Oral Xiao-xian decoction combined with AAT significantly improved the symptoms and signs of nasal congestion, open-mouth breathing, snoring, tongue, and quality of life of AH children and may be used as a long-term treatment for AH.
本研究旨在观察消岩汤联合穴位敷贴疗法（AAT）治疗小儿腺样体肥大（AH）的临床疗效。
将 93 例 AH 患儿随机分为 3 组：AAT 组、消岩汤+AAT 组、对照组：孟鲁司特钠口服治疗。所有参与者均接受治疗 1 个月。采用中医证候评分评价临床疗效，采用阻塞性睡眠呼吸暂停-18 量表评价生活质量。
消岩汤+AAT 组患者的主要症状（鼻塞、张口呼吸、打鼾、舌象）和次要症状较治疗前明显改善。组间两两比较显示，联合治疗组的打鼾、舌象、次要症状和总有效率均优于对照组和 AAT 组。此外，治疗后张口呼吸、生活质量和复发率无差异。
口服消岩汤联合 AAT 可显著改善 AH 患儿鼻塞、张口呼吸、打鼾、舌象等症状和体征，提高生活质量，可能成为 AH 的长期治疗方法。
