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[非骨水泥型植入物与骨之间界面的生理反应]

[Physiological reactions in the interface between cementless implants and bone].

作者信息

Fröschen Frank Sebastian, Wirtz Dieter Christian, Schildberg Frank Alexander

机构信息

Klinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.

出版信息

Orthopadie (Heidelb). 2023 Mar;52(3):178-185. doi: 10.1007/s00132-023-04347-9. Epub 2023 Feb 7.

DOI:10.1007/s00132-023-04347-9
PMID:36749380
Abstract

BACKGROUND

Surgical treatment of patients with osteoarthritis of the hip and persisting symptoms under conservative therapy has become increasingly important against the background of an aging population.

OBJECTIVES

What are the physiological reactions in the interface between cementless implants and bone?

METHODS

The literature is reviewed, expert opinions and animal models are analyzed and discussed.

RESULTS

Surface coating of implants with hydroxyapatite or titanium can have positive effects on osteointegration. Additional local application of mediators might be beneficial for osteointegration in the future.

CONCLUSION

Early peri-implant bone healing directly after implantation and late remodeling of the bone-implant interface are essential for secondary implant stability.

摘要

背景

在人口老龄化的背景下,对于髋关节骨关节炎患者且在保守治疗下仍存在持续症状的手术治疗变得越来越重要。

目的

非骨水泥型植入物与骨之间的界面会发生哪些生理反应?

方法

回顾文献,分析并讨论专家意见和动物模型。

结果

用羟基磷灰石或钛对植入物进行表面涂层可对骨整合产生积极影响。未来额外局部应用介质可能有利于骨整合。

结论

植入后早期种植体周围骨愈合以及骨 - 种植体界面的后期重塑对于种植体的二次稳定性至关重要。

相似文献

1
[Physiological reactions in the interface between cementless implants and bone].[非骨水泥型植入物与骨之间界面的生理反应]
Orthopadie (Heidelb). 2023 Mar;52(3):178-185. doi: 10.1007/s00132-023-04347-9. Epub 2023 Feb 7.
2
Strontium in the bone-implant interface.骨-植入物界面中的锶
Dan Med Bull. 2011 May;58(5):B4286.
3
The bisphosphonate ibandronate accelerates osseointegration of hydroxyapatite-coated cementless implants in an animal model.双膦酸盐伊班膦酸钠可加速动物模型中羟基磷灰石涂层非骨水泥型植入物的骨整合。
J Orthop Sci. 2007 Jan;12(1):61-6. doi: 10.1007/s00776-006-1081-2. Epub 2007 Jan 31.
4
Controlled laser texturing of titanium results in reliable osteointegration.钛的可控激光纹理化可实现可靠的骨整合。
J Orthop Res. 2017 Apr;35(4):820-828. doi: 10.1002/jor.23340. Epub 2016 Jun 28.
5
Safety and efficacy of additive and subtractive surface modification of Ti6Al4V endosseous implant in goat bone.Ti6Al4V 骨内种植体在山羊骨中进行增减表面改性的安全性和有效性。
J Mech Behav Biomed Mater. 2016 Apr;57:69-87. doi: 10.1016/j.jmbbm.2015.11.019. Epub 2015 Dec 4.
6
Local bisphosphonate treatment increases fixation of hydroxyapatite-coated implants inserted with bone compaction.局部双膦酸盐治疗可提高通过骨压实插入的羟基磷灰石涂层植入物的固定效果。
J Orthop Res. 2009 Feb;27(2):189-94. doi: 10.1002/jor.20745.
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Biomechanical and morphometric analysis of hydroxyapatite-coated implants with varying crystallinity.不同结晶度的羟基磷灰石涂层植入物的生物力学和形态学分析。
J Oral Maxillofac Surg. 1999 Sep;57(9):1096-108; discussion 1108-9. doi: 10.1016/s0278-2391(99)90333-6.
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Effects of a cell adhesion molecule coating on the blasted surface of titanium implants on bone healing in the rabbit femur.细胞粘附分子涂层对兔股骨钛植入物喷砂表面骨愈合的影响。
Int J Oral Maxillofac Implants. 2007 Jul-Aug;22(4):533-41.
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[Bony ongrowth on the surface of HA-coated femoral implants: an x-ray analysis].[羟基磷灰石涂层股骨植入物表面的骨赘生长:X线分析]
Z Orthop Unfall. 2012 Feb;150(1):27-31. doi: 10.1055/s-0031-1280028. Epub 2011 Oct 18.
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Acta Chir Orthop Traumatol Cech. 2009 Jun;76(3):172-8.

本文引用的文献

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The influence of stem alignment on the bone mineral density around the Polarstem following total hip arthroplasty.柄的对线方式对全髋关节置换术后 Polarstem 周围骨密度的影响。
Arch Orthop Trauma Surg. 2023 Jun;143(6):3621-3627. doi: 10.1007/s00402-022-04607-x. Epub 2022 Sep 20.
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Development of Silver-Containing Hydroxyapatite-Coated Antimicrobial Implants for Orthopaedic and Spinal Surgery.载银羟基磷灰石涂层抗菌植入物在骨科和脊柱外科中的应用研究。
Medicina (Kaunas). 2022 Apr 6;58(4):519. doi: 10.3390/medicina58040519.
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A Ten-Year Radiostereometric Analysis of Polyethylene Wear Between Oxidized Zirconium and Cobalt Chrome Articulations in Total Hip Arthroplasty.
全髋关节置换术后氧化锆和钴铬合金关节之间聚乙烯磨损的十年放射学分析。
J Arthroplasty. 2022 Jul;37(7S):S692-S696. doi: 10.1016/j.arth.2022.02.099. Epub 2022 Mar 1.
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Patient satisfaction and total hip arthroplasty: a review.患者满意度与全髋关节置换术:综述
Arthroplasty. 2019 Sep 2;1(1):6. doi: 10.1186/s42836-019-0007-3.
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Comparison of Ceramic-on-Ceramic vs. Ceramic-on-Polyethylene for Primary Total Hip Arthroplasty: A Meta-Analysis of 15 Randomized Trials.陶瓷对陶瓷与陶瓷对聚乙烯用于初次全髋关节置换术的比较:15项随机试验的荟萃分析
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Experimental study of the effects of hypoxia simulator on osteointegration of titanium prosthesis in osteoporotic rats.缺氧模拟器对骨质疏松大鼠钛假体骨整合影响的实验研究。
BMC Musculoskelet Disord. 2021 Nov 11;22(1):944. doi: 10.1186/s12891-021-04777-6.
7
Use of a Plasma-Sprayed Titanium-Hydroxyapatite Femoral Stem in Hip Arthroplasty in Patients Older than 70 Years. Is Cementless Fixation a Reliable Option in the Elderly?70岁以上患者髋关节置换术中使用等离子喷涂钛羟基磷灰石股骨柄。非骨水泥固定对老年人来说是一种可靠的选择吗?
J Clin Med. 2021 Oct 15;10(20):4735. doi: 10.3390/jcm10204735.
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Synthesis of Silver- and Strontium-Substituted Hydroxyapatite with Combined Osteogenic and Antibacterial Activities.银和锶取代的具有成骨和抗菌活性的羟基磷灰石的合成。
Biol Trace Elem Res. 2022 Feb;200(2):931-942. doi: 10.1007/s12011-021-02697-z. Epub 2021 Apr 2.
9
Cobalt-Induced Toxicity and Spasticity Secondary to Hip Arthroplasty: Case Report and Review of the Literature.钴诱导的毒性及髋关节置换术后痉挛:病例报告与文献综述
Cureus. 2020 Dec 29;12(12):e12368. doi: 10.7759/cureus.12368.
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Bone and Cartilage Interfaces With Orthopedic Implants: A Literature Review.骨科植入物与骨和软骨的界面:文献综述
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