Ishii A, Hamada H, Takayanagi M, Hayashi K
Department of Obstetrics and Gynecology, St. Marianna University, Kanagawa, Japan.
Arch Gynecol Obstet. 1987;241(1):1-8. doi: 10.1007/BF00931434.
Activities of DNA polymerase alpha and beta were assayed in crude extracts prepared from human placenta. Polymerase alpha activity was high in early pregnancy but low during the 2nd trimester. Polymerase beta activity did not change significantly with gestational weeks. The increase in polymerase alpha activity in early pregnancy may be closely related to mitosis at the time of placental formation; there might also be some type of accelerating factor for polymerase in early pregnancy.
对从人胎盘中制备的粗提物进行了DNA聚合酶α和β活性的测定。聚合酶α活性在妊娠早期较高，但在妊娠中期较低。聚合酶β活性随孕周无明显变化。妊娠早期聚合酶α活性的增加可能与胎盘形成时的有丝分裂密切相关；妊娠早期可能还存在某种类型的聚合酶加速因子。
