Boers M, Croonen A M, Dijkmans B A, Breedveld F C, Eulderink F, Cats A, Weening J J
Department of Rheumatology, Leiden University, The Netherlands.
Ann Rheum Dis. 1987 Sep;46(9):658-63. doi: 10.1136/ard.46.9.658.
Renal abnormalities in 132 necropsied patients with rheumatoid arthritis were studied. Clinical findings before death included extra-articular manifestations of the disease (86% of patients), systemic vasculitis (6%), and uraemia (23%). Necropsy findings included nephrosclerosis (90%), systemic vasculitis (14%) with kidney involvement in 8%, amyloidosis (11%), membranous glomerulopathy (8%), and focal glomerular disease (8%). Association with clinical data suggests that both rheumatoid and non-rheumatoid disease may play a part in the cause of these abnormalities.
对132例类风湿性关节炎尸检患者的肾脏异常情况进行了研究。死亡前的临床发现包括该疾病的关节外表现（86%的患者）、系统性血管炎（6%）和尿毒症（23%）。尸检结果包括肾硬化（90%）、系统性血管炎（14%），其中8%累及肾脏、淀粉样变性（11%）、膜性肾小球病（8%）和局灶性肾小球疾病（8%）。与临床数据的关联表明，类风湿性疾病和非类风湿性疾病可能在这些异常情况的病因中都起作用。
