梅毒螺旋体免疫粘连试验用于梅毒血清学诊断。2：与玻片试验、梅毒螺旋体血凝试验及荧光螺旋体抗体吸收试验的比较
Treponema pallidum immune adherence test for serodiagnosis of syphilis. 2: Comparison with glass plate, TPHA, and FTA-ABS tests.
作者信息
Tanaka S, Suzuki T, Numata T, Tsuyuki K
出版信息
Br J Vener Dis. 1978 Dec;54(6):374-9. doi: 10.1136/sti.54.6.374.
Using sera from 340 patients with syphilis the Treponema pallidum immune adherence (TPIA) test was compared with the glass plate, T. pallidum haemagglutination (TPHA), and fluorescent treponemal antibody-absorbed (FTA-ABS) tests. The results of the TPIA test agreed with those of the glass plate, TPHA, and FTA-ABS tests in 65%, 82%, and 73% of cases respectively. In the quantitative TPIA test no significant correlation with the other tests was observed, and it is, therefore, concluded that the TPIA test has highly individual characteristics. From gel filtration the particular feature of the test was its high sensitivity to the IgM antibody. The TPIA test thus appears to be suitable for estimating antibody in the early stages of the disease.
利用340例梅毒患者的血清，对梅毒螺旋体免疫黏附（TPIA）试验与玻片试验、梅毒螺旋体血凝（TPHA）试验及荧光螺旋体抗体吸收（FTA - ABS）试验进行了比较。TPIA试验结果分别与玻片试验、TPHA试验及FTA - ABS试验结果相符的病例数占比为65%、82%和73%。在定量TPIA试验中，未观察到与其他试验有显著相关性，因此得出结论，TPIA试验具有高度个体特征。从凝胶过滤结果来看，该试验的特别之处在于对IgM抗体高度敏感。因此，TPIA试验似乎适用于评估疾病早期的抗体情况。
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