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[巴西人群中年轻成年口腔鳞状细胞癌患者的生存率]

[Survival of young adults with oral squamous cell carcinoma in a brazilian population].

作者信息

Amorim Marília de Matos, Leite Maria C Silva, Alves Lisia Daltro Borges, Silva Carlos A Lima da, Santos Jean Nunes Dos, Freitas Valéria Souza

机构信息

MA: OD. M.Sc. Saúde Coletiva. Feira de Santana. Bahia, Brasil.

ML: OD. Universidade Estadual de Feira de Santana. Bahia, Brasil.

出版信息

Rev Salud Publica (Bogota). 2019 Sep 1;21(5):534-540. doi: 10.15446/rsap.V21n5.76193.

Abstract

OBJECTIVE

To analyze the profile and survival in young adults with oral squamous cell carcinoma, attended at the High Complexity in Oncology of Feira de Santana, Brazil, between 2010 and 2016.

METHODS

Retrospective cohort, performed through the information of the medical records of all young patients attended in the referred center. Descriptive analysis of the variables, Fisher's exact test, Kaplan-Meier curve and log-rank test were performed.

RESULTS

A total of 35 patients were registered. The majority were male, smokers and former alcoholics. Tumors were predominantly localized in the tongue, diagnosed at late stages, classified as well differentiated and treated mainly with surgery associated to radiotherapy and chemotherapy. The median survival time was 31 months and 22.8% of the patients died. The variables that presented statistical significance in relation to the survival time were the tumor site and the type of treatment.

CONCLUSION

The profile and low survival time reflect the need for greater attention to the disease in this population.

摘要

目的

分析2010年至2016年期间在巴西费拉德桑塔纳肿瘤高复杂性中心就诊的年轻口腔鳞状细胞癌患者的概况和生存率。

方法

回顾性队列研究,通过该转诊中心所有年轻患者的病历信息进行。对变量进行描述性分析、Fisher精确检验、Kaplan-Meier曲线分析和对数秩检验。

结果

共登记了35例患者。大多数为男性,吸烟者和既往酗酒者。肿瘤主要位于舌部,诊断时多为晚期,分类为高分化,主要采用手术联合放疗和化疗进行治疗。中位生存时间为31个月,22.8%的患者死亡。与生存时间具有统计学意义的变量是肿瘤部位和治疗类型。

结论

该人群的概况和低生存时间反映出需要对这种疾病给予更多关注。

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