结直肠癌肝转移的移植治疗。

Transplant for colorectal cancer liver metastases.

机构信息

Division of Transplantation, Department of Transplant Surgery, University of Cincinnati, OH.

Division of Transplantation, Department of Transplant Surgery, University of Cincinnati, OH. Electronic address: https://twitter.com/SJHartmanMD.

出版信息

Surgery. 2023 Jul;174(1):106-107. doi: 10.1016/j.surg.2023.01.005. Epub 2023 Feb 6.

DOI:10.1016/j.surg.2023.01.005

PMID:36754741

Abstract

Colorectal cancer with unresectable liver metastases has significant mortality when treated with chemotherapy alone. In appropriately selected patients, liver transplant is emerging as a treatment alternative for this population. Some key clinical trials, including SECA-I and SECA-II, have shown promising survival results: more trials are being conducted to evaluate safety of this practice.

摘要

结直肠癌伴无法切除的肝转移患者单独接受化疗时死亡率较高。在选择适当的患者中，肝移植作为该人群的治疗选择正在出现。一些关键的临床试验，包括 SECA-I 和 SECA-II，已经显示出有希望的生存结果：正在进行更多的试验来评估这种做法的安全性。