Parasin Nichapa, Amnuaylojaroen Teerachai, Saokaew Surasak
School of Allied Health Science, University of Phayao, Phayao, Thailand, 56000.
School of Energy and Environment, University of Phayao, Phayao, Thailand, 56000.
Eur J Pediatr. 2023 Apr;182(4):1495-1504. doi: 10.1007/s00431-023-04834-3. Epub 2023 Feb 9.
Air pollution exposure has been related to negative gross motor development in children. However, there is currently a lack of conclusive evidence for such a relationship. We carried out a systematic review and meta-analysis using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria to examine whether exposure to air pollution has an impact on children's gross motor development. Of the 9746 papers found, 7 studies examined the impact of air pollutant characteristics, such as PM, PM, and NO, on children's gross motor development. The results of the study reveal a significant association between air pollutants and an increased likelihood of negative gross motor development. PM was discovered to be considerably riskier for children's gross motor development (effect: - 1.83, 95% CI: - 3.04, - 0.62, p value = 0.002). Additionally, NO exhibited indications of a tendency to be connected to a detrimental impact on children's gross motor development (effect - 0.18, 95% CI: - 0.42, 0.07, p value = 0.097). Conclusion: Our study indicates that exposure to PM, PM, and NO, especially PM and PM, is negatively associated with children's gross motor development. However, further research is required to determine how exposure to prenatal air pollution affects children's gross motor development. What is Known - What is New: • In this study, we provide an overview of emerging data related to PM10, PM2.5, and NO2 exposure in child development, especially on the gross motor function that continues to emerge, and key findings are highlighted. • Additionally, we summarize the evidence on the underlying effect of air pollution on gross motor function from human studies.. • Overall, we emphasize that evidence from human studies is critical in suggesting detrimental child health outcomes of an action to promote preventive strategies that will effectively protect children's health..
接触空气污染与儿童粗大运动发育不良有关。然而，目前尚无确凿证据证明这种关系。我们使用系统评价和Meta分析的首选报告项目（PRISMA）标准进行了一项系统评价和Meta分析，以研究接触空气污染是否会对儿童的粗大运动发育产生影响。在找到的9746篇论文中，有7项研究考察了空气污染物特征（如PM、PM和NO）对儿童粗大运动发育的影响。研究结果显示，空气污染物与粗大运动发育不良可能性增加之间存在显著关联。发现PM对儿童粗大运动发育的风险要高得多（效应：-1.83，95%CI：-3.04，-0.62，p值=0.002）。此外，NO显示出与对儿童粗大运动发育产生有害影响有关的趋势迹象（效应-0.18，95%CI：-0.42，0.07，p值=0.097）。结论：我们的研究表明，接触PM、PM和NO，尤其是PM和PM，与儿童粗大运动发育呈负相关。然而，需要进一步研究以确定产前接触空气污染如何影响儿童的粗大运动发育。已知与新知：• 在本研究中，我们概述了与儿童发育过程中接触PM10、PM2.5和NO2相关的新数据，特别是对持续出现的粗大运动功能的影响，并突出了关键发现。• 此外，我们总结了来自人体研究的关于空气污染对粗大运动功能潜在影响的证据。• 总体而言，我们强调人体研究的证据对于提示某项行动对儿童健康有害的结果至关重要，以促进能有效保护儿童健康的预防策略。
