Eredics Klaus, Drerup Martin, Özsoy Mehmet, Wehrberger Clemens, Lenz Matthias, Ramesmayer Christian, Stolzlechner Philipp, Zanier Johannes, Falkensammer Claudia E, Handjiev Ivan, Wasserscheid Andreas, Seklehner Stephan
Department of Urology, Paracelsus Medizinische Privatuniversität Salzburg, Strubergasse 21, 5020, Salzburg, Austria.
Department of Urology, Klinik Donaustadt, Langobardenstraße 122, 1220, Vienna, Austria.
World J Urol. 2023 Mar;41(3):849-856. doi: 10.1007/s00345-023-04304-3. Epub 2023 Feb 8.
To assess the contemporary in-hospital management of octogenarians and nonagenarians with renal calculi.
A multicentric retrospective evaluation of patients aged ≥ 80 years hospitalized with kidney stones between 01/2000 and 12/2019. Stone and patient related data were collected, including stone size and location, geriatric status and comorbidities. Surgical treatment patterns and outcome were assessed.
A total of 299 patients (57% female) with kidney stones were analyzed. Mean age was 84.7 years. Patients were largely multimorbid (ASA ≥ 3 in 70%) and about 25% were classified as frail. Active stone treatment was performed in 65% and 35% were treated with urinary diversion (stent or nephrostomy). Prognostic factors for receiving an active stone treatment were age < 90 years, male sex, stone size and quantity, and performance status. Mean overall survival was 23.7 months and when stratified to treatment mean survival were 21 months after urinary diversion, 28 months after URS, 29 months after PCNL and 45 months after SWL.
Age, frailty and performance-status as well as stone size and quantity are predictors for active stone treatment. Octogenarians and nonagenarians, who are considered fit for surgery, tend to live long enough to profit from active stone treatment.
评估当代80岁及90岁以上肾结石患者的住院治疗情况。
对2000年1月至2019年12月期间因肾结石住院的年龄≥80岁的患者进行多中心回顾性评估。收集结石及患者相关数据,包括结石大小和位置、老年状态及合并症。评估手术治疗方式及结果。
共分析了299例肾结石患者(57%为女性)。平均年龄为84.7岁。患者大多患有多种疾病(70%的美国麻醉医师协会身体状况分级≥3级),约25%被归类为体弱。65%的患者接受了积极的结石治疗,35%的患者接受了尿液改道治疗(放置支架或肾造瘘)。接受积极结石治疗的预后因素包括年龄<90岁、男性、结石大小和数量以及身体状况。平均总生存期为23.7个月,按治疗方式分层后,尿液改道后的平均生存期为21个月,输尿管镜碎石术后为28个月,经皮肾镜取石术后为29个月,体外冲击波碎石术后为45个月。
年龄、体弱程度和身体状况以及结石大小和数量是积极结石治疗的预测因素。被认为适合手术的80岁及90岁以上患者往往寿命足够长,能够从积极的结石治疗中获益。