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基于优选显著特征的慢性肾脏病早期检测和诊断。

Early Detection and Diagnosis of Chronic Kidney Disease Based on Selected Predominant Features.

机构信息

Department of Information Systems, Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah, Saudi Arabia.

Department of Computer Sciences, College of Computer and Information Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.

出版信息

J Healthc Eng. 2023 Jan 30;2023:3553216. doi: 10.1155/2023/3553216. eCollection 2023.

Abstract

In numerous perilous cases, a quick medical decision is needed for the early detection of chronic diseases to avoid austere consequences that may be fatal. Chronic kidney disease (CKD) is a prevalent disease that presents a variety of challenges, including soaring costs for intervention, urgency, and, more importantly, difficulty in early detection of the disease. The current study carries out a prediction-based method that helps in detecting and diagnosing CKD patients which enables a fast and accurate decision-making process at the early stage. A combination of preprocessing and feature selection methods was developed; additionally, several prediction models, such as K-nearest neighbor (KNN), support vector machine (SVM), random forest (RF), and bagging, were trained based on the processed dataset. The performance evaluation shows higher reliability of all models in terms of accuracy, precision, sensitivity, F-measure, specificity, and area under the curve (AUC) score. Specifically, KNN outperformed with an accuracy of 99.50%, sensitivity of 99.2%, precision of 100%, specificity of 98.7%, and F-measure and AUC score of 99.6%. The experimental results of KNN show the best fitted model compared to the existing state-of-the-art methods. Moreover, the reduced feature set proves that just a few clinical tests are enough to detect CKD, resulting in diagnosis cost reduction.

摘要

在许多危险的情况下,需要快速做出医疗决策,以便早期发现慢性病,避免可能致命的严重后果。慢性肾脏病(CKD)是一种常见疾病,它带来了多种挑战,包括干预成本的飙升、紧迫性,更重要的是,早期发现疾病的难度。本研究采用基于预测的方法来帮助检测和诊断 CKD 患者,从而在早期实现快速、准确的决策过程。该方法结合了预处理和特征选择方法,还基于处理后的数据集训练了几种预测模型,如 K-最近邻(KNN)、支持向量机(SVM)、随机森林(RF)和袋装。性能评估表明,所有模型在准确性、精度、灵敏度、F 值、特异性和曲线下面积(AUC)评分方面都具有更高的可靠性。具体来说,KNN 的准确率为 99.50%,灵敏度为 99.2%,精度为 100%,特异性为 98.7%,F 值和 AUC 得分为 99.6%。与现有的最先进方法相比,KNN 的实验结果表明它是最佳拟合模型。此外,简化的特征集证明,只需要几个临床测试就足以检测 CKD,从而降低诊断成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ea/9902122/e4a3a384d12a/JHE2023-3553216.001.jpg

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