Ullah Zahid, Jamjoom Mona, Thirumalaisamy Manikandan, Alajmani Samah H, Saleem Farrukh, Sheikh-Akbari Akbar, Khan Usman Ali
Information Systems Department, College of Computer and Information Sciences, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
Department of Computer Sciences, College of Computer and Information Sciences, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Biomed Eng Comput Biol. 2024 Sep 4;15:11795972241277322. doi: 10.1177/11795972241277322. eCollection 2024.
Brain tumor (BT) is an awful disease and one of the foremost causes of death in human beings. BT develops mainly in 2 stages and varies by volume, form, and structure, and can be cured with special clinical procedures such as chemotherapy, radiotherapy, and surgical mediation. With revolutionary advancements in radiomics and research in medical imaging in the past few years, computer-aided diagnostic systems (CAD), especially deep learning, have played a key role in the automatic detection and diagnosing of various diseases and significantly provided accurate decision support systems for medical clinicians. Thus, convolution neural network (CNN) is a commonly utilized methodology developed for detecting various diseases from medical images because it is capable of extracting distinct features from an image under investigation. In this study, a deep learning approach is utilized to extricate distinct features from brain images in order to detect BT. Hence, CNN from scratch and transfer learning models (VGG-16, VGG-19, and LeNet-5) are developed and tested on brain images to build an intelligent decision support system for detecting BT. Since deep learning models require large volumes of data, data augmentation is used to populate the existing dataset synthetically in order to utilize the best fit detecting models. Hyperparameter tuning was conducted to set the optimum parameters for training the models. The achieved results show that VGG models outperformed others with an accuracy rate of 99.24%, average precision of 99%, average recall of 99%, average specificity of 99%, and average 1-score of 99% each. The results of the proposed models compared to the other state-of-the-art models in the literature show better performance of the proposed models in terms of accuracy, sensitivity, specificity, and 1-score. Moreover, comparative analysis shows that the proposed models are reliable in that they can be used for detecting BT as well as helping medical practitioners to diagnose BT.
脑肿瘤(BT)是一种可怕的疾病,也是人类主要的死亡原因之一。脑肿瘤主要分两个阶段发展,其体积、形态和结构各不相同,可以通过化疗、放疗和手术干预等特殊临床程序进行治疗。随着过去几年放射组学的革命性进展和医学成像研究的发展,计算机辅助诊断系统(CAD),尤其是深度学习,在各种疾病的自动检测和诊断中发挥了关键作用,并显著为医学临床医生提供了准确的决策支持系统。因此,卷积神经网络(CNN)是一种常用的方法,用于从医学图像中检测各种疾病,因为它能够从所研究的图像中提取独特的特征。在本研究中,采用深度学习方法从脑图像中提取独特特征以检测脑肿瘤。因此,从头开始构建了CNN以及迁移学习模型(VGG - 16、VGG - 19和LeNet - 5),并在脑图像上进行测试,以建立一个用于检测脑肿瘤的智能决策支持系统。由于深度学习模型需要大量数据,因此使用数据增强来综合扩充现有数据集,以便利用最合适的检测模型。进行了超参数调整以设置训练模型的最佳参数。所取得的结果表明,VGG模型表现优于其他模型,准确率为99.24%,平均精度为99%,平均召回率为99%,平均特异性为99%,平均F1分数均为99%。与文献中其他最先进模型相比,所提出模型的结果表明,在准确率、灵敏度、特异性和F1分数方面,所提出的模型具有更好的性能。此外,对比分析表明,所提出的模型是可靠的,因为它们可用于检测脑肿瘤以及帮助医学从业者诊断脑肿瘤。